PERBEDAAN KADAR KOLESTEROL LDL DARAH TIKUS SPRAGUE DAWLEY PADA PEMBERIAN KOPI FILTER DAN TANPA FILTER

Raysa Tanjung Sari; Niken Puruhita

doi:10.14710/jnc.v1i1.403

DOI: https://doi.org/10.14710/jnc.v1i1.403

PERBEDAAN KADAR KOLESTEROL LDL DARAH TIKUS SPRAGUE DAWLEY PADA PEMBERIAN KOPI FILTER DAN TANPA FILTER

Raysa Tanjung Sari , Niken Puruhita

Program Studi Ilmu Gizi Fakultas Kedokteran Universitas Diponegoro, Indonesia

Published: .

Citation Format:

Abstract

Background : Coffee contains cafestol and kahweol which can increase LDL cholesterol levels. Effect of cafestol and kahweol with chlorogenic acids are antagonist in coffee. Chlorogenic acids is strong antioxidant in coffee. Unfiltered coffee contains more chlorogenic acids and cafestol than filtered coffee. The study aims to determine the differences of LDL cholesterol levels of Sprague Dawley rats in giving filtered and unfiltered coffee.

Methods : a laboratory experimental study, with randomized pre-post test control group design, with a simple random sampling to 28 Sprague Dawley rats were divided into 3 groups. The first treatment was given unfiltered coffee 4x2.7 ml, the second treatment was given filtered coffee 4x2.7 ml and the control was given water 4x2.7 ml for 28 days. LDL cholesterol levels were determined by the homogenous enzyme method. Data were analyzed by paired t-test and Oneway ANOVA test at 95% confident level.

Results : Changes levels of LDL cholesterol in filtered coffee (0.85 mg/dl) are higher than unfiltered coffee (0.15 mg/dl). However statistical test shows there is no significant difference of LDL cholesterol in filtered and unfiltered coffee (p>0.05).

Conclusion : There is no significant difference of LDL cholesterol levels of Sprague Dawley rats in filtered and unfiltered coffee.

Fulltext View|Download

Keywords: unfiltered coffee; filtered coffee; LDL cholesterol; Sprague Dawley rats

Article Metrics:

Article Info

Section: Jilid 1

Language : EN

In Vol 1, No 1 (2012): Oktober 2012

Recent articles

FAKTOR-FAKTOR YANG MEMPENGARUHI TINGKAT KESEGARAN PADA WANITA VEGETARIAN KEPATUHAN KONSUMSI TABLET BESI FOLAT PADA IBU HAMIL DAN FAKTOR YANG MEMPENGARUHI ASUPAN TINGGI NATRIUM DAN BERAT BADAN LAHIR SEBAGAI FAKTOR RISIKO KEJADIAN HIPERTENSI OBESITAS PADA REMAJA AWAL GAMBARAN KEBIASAAN KONSUMSI MIE INSTAN PADA ANAK USIA 7-12 TAHUN Studi di Sekolah Dasar Kanisius Tlogosari Kulon Semarang HUBUNGAN ANTARA BEBERAPA INDIKATOR STATUS GIZI DENGAN TEKANAN DARAH PADA REMAJA PENGARUH PEMBERIAN BUAH PEPAYA (CARICA PAPAYA L.) TERHADAP KADAR TRIGLISERIDA PADA TIKUS SPRAGUE DAWLEY DENGAN HIPERKOLESTEROLEMIA PENGARUH PEMBERIAN KEFIR SUSU SAPI TERHADAP KADAR TRIGLISERIDA TIKUS JANTAN SPRAGUE DAWLEY PERBEDAAN KARAKTERISTIK USIA, ASUPAN MAKANAN, AKTIVITAS FISIK, TINGKAT SOSIAL EKONOMI DAN PENGETAHUAN GIZI PADA WANITA DEWASA DENGAN KELEBIHAN BERAT BADAN ANTARA DI DESA DAN KOTA PENGARUH SUBSTITUSI TEPUNG TERIGU DENGAN TEPUNG TEMPE DAN TEPUNG UBI JALAR KUNING TERHADAP KADAR PROTEIN, KADAR Β-KAROTEN, DAN MUTU ORGANOLEPTIK ROTI MANIS PENGARUH PEMBERIAN MAKANAN TAMBAHAN PEMULIHAN (PMT-P) TERHADAP STATUS GIZI BALITA GIZI BURUK DI DINAS KESEHATAN KOTA SEMARANG TAHUN 2012 More recent articles

Last update:

No citation recorded.

Last update:

No citation recorded.

The Authors submitting a manuscript do so on the understanding that if accepted for publication, copyright of the article shall be assigned to Journal of Nutrition College and Department of Nutrition Science, Faculty of Medicine, Universitas Diponegoro as publisher of the journal.

Copyright encompasses exclusive rights to reproduce and deliver the article in all form and media, including reprints, photographs, microfilms and any other similar reproductions, as well as translations. The reproduction of any part of this journal, its storage in databases and its transmission by any form or media, such as electronic, electrostatic and mechanical copies, photocopies, recordings, magnetic media, etc., will be allowed only with a written permission from Journal of Nutrition College.

Journal of Nutrition College, Faculty of Medicine, Universitas Diponegoro, the Editors and the Advisory Editorial Board make every effort to ensure that no wrong or misleading data, opinions or statements be published in the journal. In any way, the contents of the articles and advertisements published in Journal of Nutrition College are sole and exclusive responsibility of their respective authors and advertisers.