PENGARUH PEMBERIAN SARI DAUN CINCAU HIJAU  (PREMNA OBLONGIFOLIA MERR) TERHADAP KADAR KOLESTEROL HDL DAN KOLESTEROL LDL TIKUS SPRAGUE DAWLEY DISLIPIDEMIA

Ananda Eka Astirani; Hesti Murwani Rahayuningsih

doi:10.14710/jnc.v1i1.514

DOI: https://doi.org/10.14710/jnc.v1i1.514

PENGARUH PEMBERIAN SARI DAUN CINCAU HIJAU (PREMNA OBLONGIFOLIA MERR) TERHADAP KADAR KOLESTEROL HDL DAN KOLESTEROL LDL TIKUS SPRAGUE DAWLEY DISLIPIDEMIA

Ananda Eka Astirani¹ , Hesti Murwani Rahayuningsih²

¹Mahasiswa Program Studi Ilmu Gizi Fakultas Kedokteran Universitas Diponegoro, Indonesia

²Program Studi Ilmu Gizi Fakultas Kedokteran Universitas Diponegoro, Indonesia

Published: 1 Oct 2012.

BibTex Citation Data :

@article{JNC514,
    author = {Ananda Astirani and Hesti Rahayuningsih},
    title = {PENGARUH PEMBERIAN SARI DAUN CINCAU HIJAU  (PREMNA OBLONGIFOLIA MERR) TERHADAP KADAR KOLESTEROL HDL DAN KOLESTEROL LDL TIKUS SPRAGUE DAWLEY DISLIPIDEMIA},
    journal = {Journal of Nutrition College},
  volume = {1},
    number = {1},
    year = {2012},
    keywords = {green grass jelly, HDL cholesterol, LDL cholesterol, dyslipidemia},
    abstract = {  Background  :    Dyslipidemia is an increase in total cholesterol, LDL-cholesterol and triglycerides and also decrease HDL-cholesterol concentration from normal range. Restricting fat consumption, increasing intake of fruits and vegetables rich in fiber and antioxidant can help manage dyslipidemia. Green grass jelly (Premna oblongifolia Merr) rich in fiber and chlorophyll which can increase HDL-cholesterol and decrease LDL cholesterol.      Objective  :    to analyze the effect of green grass jelly extract on HDL-cholesterol and LDL-cholesterol alteration.     Methods  :    This research was experimental laboratory using pre-post test with randomized control groups design. Sample were male Sprague Dawley rats, 7-8 weeks old, inducted dyslipidemia, given green grass jelly diet using 2,7 ml and 5,4 ml dosage for 28 days. HDL-cholesterol and LDL-cholesterol were measured by CHOD-PAP and diasis reagent. Normality data were tested by Saphiro Wilk test. Data were analyzed by paired t test/wilcoxon and Anova/ Kruskal wallis.     Result  :    Green grass jelly (Premna oblongifolia Merr) extract 5,4 ml/day can significantly increase HDL-cholesterol in Sprague dawley dyslipidemia rats from   22,29±4,82 mg/dl to 27,29±3,82 mg/dl (p<0,05)   but have no effect for decreasing LDL-cholesterol serum.      Conclusion  :    Green grass jelly (Premna oblongifolia Merr) extract 5,4 ml/day can significantly increase HDL-cholesterol in Sprague dawley dyslipidemia rats for about 22%.  },
   issn = {2622-884X},   pages = {265--272}  doi = {10.14710/jnc.v1i1.514},
    url = {https://ejournal3.undip.ac.id/index.php/jnc/article/view/514}
}

Citation Format:

Abstract

Background : Dyslipidemia is an increase in total cholesterol, LDL-cholesterol and triglycerides and also decrease HDL-cholesterol concentration from normal range. Restricting fat consumption, increasing intake of fruits and vegetables rich in fiber and antioxidant can help manage dyslipidemia. Green grass jelly (Premna oblongifolia Merr) rich in fiber and chlorophyll which can increase HDL-cholesterol and decrease LDL cholesterol.

Objective : to analyze the effect of green grass jelly extract on HDL-cholesterol and LDL-cholesterol alteration.

Methods : This research was experimental laboratory using pre-post test with randomized control groups design. Sample were male Sprague Dawley rats, 7-8 weeks old, inducted dyslipidemia, given green grass jelly diet using 2,7 ml and 5,4 ml dosage for 28 days. HDL-cholesterol and LDL-cholesterol were measured by CHOD-PAP and diasis reagent. Normality data were tested by Saphiro Wilk test. Data were analyzed by paired t test/wilcoxon and Anova/ Kruskal wallis.

Result : Green grass jelly (Premna oblongifolia Merr) extract 5,4 ml/day can significantly increase HDL-cholesterol in Sprague dawley dyslipidemia rats from 22,29±4,82 mg/dl to 27,29±3,82 mg/dl (p<0,05) but have no effect for decreasing LDL-cholesterol serum.

Conclusion : Green grass jelly (Premna oblongifolia Merr) extract 5,4 ml/day can significantly increase HDL-cholesterol in Sprague dawley dyslipidemia rats for about 22%.

Fulltext View|Download

Keywords: green grass jelly, HDL cholesterol, LDL cholesterol, dyslipidemia

Article Metrics:

Article Info

Section: Jilid 4

Language : EN

In Vol 1, No 1 (2012): Oktober 2012

Recent articles

FAKTOR RISIKO HIPERTENSI DITINJAU DARI KEBIASAAN MINUM KOPI (Studi Kasus di Wilayah Kerja Puskesmas Ungaran pada Bulan Januari-Februari 2012) FAKTOR RISIKO KEJADIAN STUNTING PADA ANAK USIA 12-36 BULAN DI KECAMATAN PATI, KABUPATEN PATI HUBUNGAN PENGETAHUAN, SIKAP, DAN MOTIVASI DENGAN KEPATUHAN KONSUMSI TABLET BESI FOLAT PADA IBU HAMIL PERBEDAAN KONSUMSI CAIRAN DAN STATUS HIDRASI PADA REMAJA OBESITAS DAN NON OBESITAS PENGARUH PEMBERIAN JUS LIDAH BUAYA (ALOE VERA) TERHADAP KADAR KOLESTEROL LOW DENSITY LIPOPROTEIN (LDL) DAN HIGH DENSITY LIPOPROTEIN (HDL) PENGARUH ASUPAN MAKAN (ENERGI, KARBOHIDRAT, PROTEIN DAN LEMAK) TERHADAP DAYA TAHAN JANTUNG PARU (VO2 MAKS) ATLET SEPAK BOLA PENGARUH PEMBERIAN SUSU KEDELAI TERHADAP KADAR GLUKOSA DARAH PUASA PADA WANITA PREDIABETES PENGARUH PEMBERIAN KEFIR SUSU SAPI TERHADAP KADAR TRIGLISERIDA TIKUS JANTAN SPRAGUE DAWLEY ASUPAN TINGGI LEMAK DAN AKTIVITAS OLAHRAGA SEBAGAI FAKTOR RISIKO TERJADINYA HIPERTENSI OBESITIK PADA REMAJA AWAL PENGARUH PEMBERIAN JUS TOMAT (LYCOPERSICUM COMMUNE) TERHADAP TEKANAN DARAH WANITA POSTMENOPAUSE HIPERTENSIF More recent articles

Last update:

No citation recorded.

Last update:

No citation recorded.

The Authors submitting a manuscript do so on the understanding that if accepted for publication, copyright of the article shall be assigned to Journal of Nutrition College and Department of Nutrition Science, Faculty of Medicine, Universitas Diponegoro as publisher of the journal.

Copyright encompasses exclusive rights to reproduce and deliver the article in all form and media, including reprints, photographs, microfilms and any other similar reproductions, as well as translations. The reproduction of any part of this journal, its storage in databases and its transmission by any form or media, such as electronic, electrostatic and mechanical copies, photocopies, recordings, magnetic media, etc., will be allowed only with a written permission from Journal of Nutrition College.

Journal of Nutrition College, Faculty of Medicine, Universitas Diponegoro, the Editors and the Advisory Editorial Board make every effort to ensure that no wrong or misleading data, opinions or statements be published in the journal. In any way, the contents of the articles and advertisements published in Journal of Nutrition College are sole and exclusive responsibility of their respective authors and advertisers.