DOI: https://doi.org/10.14710/jnc.v11i1.32573

PENGARUH PEMBERIAN KURMA AJWA (PHOENIX DACTYLIFERA) TERHADAP TEKANAN DARAH PADA LANSIA

1Departemen Ilmu Gizi, Fakultas Kedokteran, Universitas Diponegoro, Indonesia

2Departemen Kedokteran, Fakultas Kedokteran, Universitas Diponegoro, Indonesia

Received: 9 Dec 2021; Published: 31 Jan 2022.

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Abstract

Latar Belakang: Hipertensi merupakan faktor risiko utama terjadinya penyakit kardiovaskuler dan menjadi salah satu beban kesehatan global yang paling penting. Kurma Ajwa memiliki kandungan flavonoid yang diketahui memiliki efek menurunkan tekanan darah.

Tujuan: Penelitian ini bertujuan mengetahui pengaruh pemberian kurma Ajwa terhadap tekanan darah dengan mengetahui perbedaan penurunan tekanan darah setelah pemberian kurma Ajwa antara kelompok perlakuan dan kelompok kontrol.

Metode: Desain penelitian ini menggunakan Randomized Controlled Trial (RCT) dua kelompok dengan teknik systematic random sampling. Sebanyak 40 subjek berusia >60 tahun ikut dalam penelitian ini. Subjek secara acak dibagi menjadi dua kelompok: kelompok perlakuan yang menerima intervensi kurma Ajwa (20 sampel) dan yang lainnya adalah kelompok kontrol (20 sampel). Pengumpulan data dilakukan dengan wawancara, pengukuran tekanan darah, dan pengukuran antropometri. Tekanan darah diukur sebelum, selama dan sesudah pemberian kurma Ajwa 100 g / hari selama 6 minggu. Data dianalisis dengan independent t test, uji Mann-Whitney, Wilcoxon, dan ANCOVA.

Hasil: Terdapat perbedaan penurunan tekanan darah sistolik (p < 0,001) dan diastolik (p < 0,001) setelah pemberian kurma Ajwa antara kelompok perlakuan dan kelompok kontrol . Tekanan darah sistolik dan diastolik pada kelompok perlakuan rata-rata turun sebesar 14 mmHg dan 8,5 mmHg. Tidak ada variabel perancu yang berpengaruh signifikan terhadap penurunan tekanan darah dalam penelitian ini.

Simpulan: Pemberian kurma Ajwa 100 g / hari selama 6 minggu berpengaruh signifikan terhadap penurunan tekanan darah pada lansia.

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Keywords: Kurma Ajwa, Tekanan Darah, Lansia

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  1. Barbeau T. Cardiovascular physiology. Francis Marion University; 2004
  2. Fitriani N, Nilamsari N. Factors associated with blood pressure on shift workers and non-shift workers in PT. X Gresik. J Ind Hyg Occup Heal. 2017;2(1):57–75. https://doi.org/ 10.21111/jihoh.v2i1.1273
  3. Kemenkes RI Pusat Data dan Informasi. Hipertensi. Jakarta; Kemenkes: 2014
  4. Mozaffarian D, Benjamin E, Go A. Heart disease and stroke statistics. Circulation. 2015;131:29–322. https://doi.org/10.1161/CIR.0000000000000152
  5. Suhadi R. Seluk beluk hipertensi: Peningkatan kompetensi klinis untuk pelayanan kefarmasian. Yogyakarta: Sanata Dharma University Press; 2016
  6. WHO. World Mortality. Geneva: WHO: 2019
  7. Djaja S. Analisis penyebab kematian dan tantangan yang dihadapi penduduk lanjut usia di Indonesia menurut riset kesehatan dasar 2007. Bul Penelit Sist Kesehat. 2012;15(4):323–30
  8. Aristi D, Rasni H, Susumaningrum L, Susanto T, Siswoyo S. Hubungan konsumsi makanan tinggi natrium dengan kejadian hipertensi pada buruh tani di wilayah kerja Puskesmas Panti Kabupaten Jember. Bul Penelit Sist Kesehat. 2020;23(1):53–60. https://doi.org/10.22435/hsr.v23i1.2741
  9. Boeing H, Bechthold A, Bub A. Critical review: vegetables and fruit in the prevention of chronic diseases. Eur J Nutr. 2012; 51(6): 637-663. https://doi.org/10.1007/s00394-012-0380-y
  10. Chun O, Chung S, Song W. Estimated dietary flavonoid intake and major food sources of U.S. adults. J Nutr. 2007;137:1244–1252. https://doi.org/10.1093/jn/137.5.1244
  11. Macready A, TW G, Chong M. Flavonoid-rich fruit and vegetables improve microvascular reactivity and inflammatory status in men at risk of cardiovascular disease – FLAVURS: a randomized controlled trial. Am J Clin Nutr. 2014; 99(3): 479-489. https://doi.org/10.3945/ajcn.113.074237
  12. Abdul-hamid NA, Hafizah N, Maulidiani M, Mediani A, Safinar I, Ling C, et al. Quality evaluation of the physical properties, phytochemicals, biological activities and proximate analysis of nine Saudi date palm fruit varieties. J Saudi Soc Agric Sci. 2020; 19(2): 151–60. https://doi.org/10.1016/j.jssas.2018.08.004
  13. Bouhoreira A, Dadamoussa B. Characterization of some flavonoids in Phoenix dactylifera L using HPLC-MS-MS. J Chem Pharm Res. 2016;8(5):169–76
  14. Eimad T, Mohamed B, Khalid S, Mohamed B, Chakib A, Younes F. Evaluation of antioxidant, antihemolytic and antibacterial potential of six Moroccan date fruit (Phoenix dactylifera L.) varieties. J King Saud Univ. 2016;28:136–42. https://doi.org/ 10.1016/j.jksus.2016.01.002
  15. Azis A, Abubakar Y, Erfiza NM. Analisis total flavonoid dan vitamin C pada beberapa jenis mentimun (Cucumis sativus L.). J lmiah Mhs Pertan Unsyiah. 2018;3(1):381–7. https://doi.org/10.17969/jimfp.v3i1.6540
  16. Clark J, Zahradka P, Taylor C. Efficacy of flavonoids in the management of high blood pressure. Nutr Rev. 2015;1–24. https://doi.org/10.1093/nutrit/nuv048
  17. Larson A, Symons J, Jalili T. Quercetin: A treatment for hypertension?—A review of efficacy and mechanisms. Pharmaceuticals. 2010;3:237–50. https://doi.org/10.3390/ph3010237
  18. Chen CK, Pace-Asciak CR. Vasorelaxing activity of resveratrol and quercetin in isolated rat aorta. Gen Pharmacol. 1996;27:363–6. https://doi.org/10.1016/0306-3623(95)02001-2
  19. Loizzo M, Said A, Tundis R, Rashed K, Statti G, Hufner A, et al. Inhibition of angiotensin converting enzyme (ACE) by flavonoids isolated from Ailanthus excelsa (Roxb) (Simaroubaceae). Phytother Res. 2007;21:32–6. https://doi.org/10.1002/ptr.2008
  20. Rivera L, Moron R, Shancez M. Quercetin ameliorates metabolic syndrome and improves the inflammatory status in obese zucker rats. Obesity (Silver Spring). 2008; 16(9): 2081-2087. https://doi.org/10.1038/oby.2008.315
  21. Husaidah S, Ikhtiar M, Nurlinda A. Pengaruh pemberian kurma Ajwa (Phoenix dactylifera) terhadap perubahan tekanan darah ibu hamil hipertensi. J Kesehat. 2019;2(1):34–43
  22. Egert S, Bosy-Westphal A, Seiberl J, et al. Quercetin reduces systolic blood pressure and plasma oxidised low-density lipoprotein concentrations in overweight subjects with a high-cardiovascular disease risk phenotype: a double-blinded, placebo-controlled cross-over study. Br J Nutr. 2009;102:1065–1074. https;//doi.org/10.1017/S0007114509359127
  23. He J, Whelton P. Elevated systolic blood pressure and risk of cardiovascular and renal disease: overview of evidence from observational epidemiologic studies and randomized controlled trials. Am Hear J. 1999;138:211–219. https://doi.org/10.1016/s0002-8703(99)70312-1
  24. Purwati D, Suryani M, Supriyono M. Perbedaan tekanan darah sebelum dan sesudah terapi relaksasi benson pada pasien hipertensi. Ejeournal Stikes Telogorejo. 2012; 1(1): 1-7
  25. Bell K, Twiggs J, Olin BR. Hypertension: The Silent Killer: Updated JNC-8 Guideline Recommendations. Alabama Pharmacy association: 2015
  26. Laurence D, Bacharach A, editors. Evaluation of Drug Activities: Pharmacometrics. London: Academic Press Inc. Ltd; 1964
  27. Nafidah N. Hubungan antara aktivitas fisik dengan tingkat kognitif lanjut usia di panti sosial tresna werdha budi mulia 4 Margaguna Jakarta Selatan. Universitas Islam Negeri Syarif Hidayatullah; Skripsi: 2014
  28. Gibson R. Principles of Nutritional Assessment. New York: Oxford University Press; 2005
  29. Sukma P, Puruhita N. Pengaruh pemberian jus tomat (Lycopersicum commune) terhadap tekanan sistole dan diastole laki-laki hipertensi usia 40-45 tahun. Journal of Nutrition College. 2015;4(2): 110-118. https://doi.org/10.14710/jnc.v4i2.10053
  30. Khoiru R, Suprihatin. Peningkatan tekanan darah setelah minum kopi dan merokok. J STIKES. 2014;7(1). 1-12
  31. Hamer M. Coffee and health: Explaining conflicting result in hypertension. J Hum Hypertens. 2006;20:909–12
  32. Triyanto E. Pelayanan Keperawatan bagi Penderita Hipertensi secara Terpadu. Yogyakarta: Graha Ilmu; 2014
  33. Marliani L. 100 Question & Answer Hipertensi. Jakarta: Elex Media Komputindo; 2007
  34. Larson A, Witman M, Guo Y. Acute, quercetin-induced reductions in blood pressure in hypertensive individuals are not secondary to lower plasma angiontensin-converting enzyme activity or endothelin-1: nitric oxide. Nutr Res. 2012; 32(8): 557-564. https://doi.org/10.1016/j.nutres.2012.06.018
  35. Vikrant S, Tiwari S. Essential hypertension - Pathogenesis and pathophysiology. J Indian Acad Clin Med. 2001;2:141–61
  36. Carretero O. Novel mechanism of action of ACE and its inhibitors. Am J Physiol Hear Circ Physiol. 2005;289:796–1797. https://doi.org/10.1152/ajpheart.00781.2005
  37. Wyld P, Grant J, Lippi A, Criscuoli M, Re G Del, Subissi A. Pharmacokinetics and biochemical efficacy of idrapril calcium, a novel ACE inhibitor, after multiple oral administration in humans. Br J Clin Pharmacol. 1994;38:421–5. https://doi.org/10.1111/j.1365-2125.1994.tb04377.x
  38. Olaleye M, Crown O, Akinmoladun A. Rutin and quercetin show greater efficacy than nifedipin in ameliorating hemodynamic, redox, and metabolite imbalances in sodium chloride-induced hypertensive rats. Human & Experimental Toxicology. 2014; 33: 602-608. https://doi.org/10.1177/0960327113504790
  39. Moradi Z, Far Ajallah M, Mohammadi M, Esfandnia F, Taovsi P, Esfandnia A. Evaluation of stress factors among the elderly. J Med Life. 2015;8:146–50
  40. Subekti R. Analisis Faktor-faktor yang Mempengaruhi Tekanan Darah pada Usia

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