DOI: https://doi.org/10.14710/jnc.v12i1.33167

VITAMIN C, VITAMIN D DAN IMUNITAS PASIEN COVID-19

Politeknik Kesehatan Kementrian Kesehatan Bengkulu, Indonesia

Received: 2 Feb 2022; Published: 23 Mar 2023.

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Abstract
Latar belakang: Pada tahun 2020 wabah Virus Corona (Covid-19) menyebar hampir di seluruh Negara. Cara untuk mengatasi Covid-19 yaitu dengan peran vitamin C dan D. Vitamin C memiliki sifat antioksidan yang mampu melindungi sel dan jaringan tubuh dari kerusakan oksidatif. Sedangkan vitamin D berperan meningkatkan innate imunity yang akan menghambat aktivitas bakteri Covid-19.

Tujuan: Penlitian ini bertujuan untuk mengkaji artikel tentang suplementasi vitamin C dan vitamin D terhadap imunitas pasien covid-19.

Metode: Penelitian ini menggunakan kajian (ulasan) literatur pada 10 artikel dengan menggunakan database Google Scholar, Pubmed dan Science Direct terbitan tahun 2019-2021. Studi ini diawali penyeleksian artikel  dengan diagram Preferred Reporting Item for Systematic and Meta-analysis (PRISMA). Kriteria yang digunakan adalah artikel yang diakses secara penuh ( full text) dalam format pdf  menggunakan bahasa Inggris dengan kata kunci vitamin C, vitamin D dan Covid-19.

Hasil: Literatur review ini menunjukkan bahwa dari 10 artikel yang terdiri masing-masing 5 artikel tentang vitamin C dan vitamin D. Pemberian suplementasi vitamin C dapat mengurangi gejala, meningkatkan kesadaran dan menurunkan risiko kematian akibat Covid-19. Suplementasi vitamin D berpengaruh terhadap lama hari rawat di rumah sakit, kebutuhan oksigen dan peningkatan serum 25(OH)D sehingga dapat mempercepat penyembuhan Covid-19.

Simpulan: Vitamin C berpengaruh dalam meningkatkan sistem imun dan berfungsi sebagai antioksidan. Vitamin D dapat berpengaruh dalam meningkatkan sistem imun bawaan dan sistem imun adaptif, sehingga dapat mempercepat penyembuhan infeksi Covid-19.

 

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Keywords: Covid 19; Imunitas; Suplemen; Vitamin C; Vitamin D

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