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The Efficacy of 0.5 Gram NaCl Capsule in the Treatment of Umbilical Granuloma in Neonates: A Case Report

*Tubagus Ferdi Fadilah orcid scopus  -  Department of Child Health, Faculty of Medicine, Universitas Trisakti, Jakarta, Indonesia, Indonesia
Nafisa Salma Wulandari  -  Undergraduate Program Faculty of Medicine, Universitas Trisakti, Indonesia, Indonesia
Nia Nurul Aziza  -  Department of Child Health, Faculty of Medicine, Universitas Trisakti, Jakarta, Indonesia, Indonesia
Dita Setiati orcid  -  Department of Child Health, Faculty of Medicine, Universitas Trisakti, Jakarta, Indonesia, Indonesia
Firda Fairuza  -  Department of Child Health, Faculty of Medicine, Universitas Trisakti, Jakarta, Indonesia, Indonesia
Nathalia Ningrum  -  Department of Child Health, Faculty of Medicine, Universitas Trisakti, Jakarta, Indonesia, Indonesia
Meiriani Sari orcid  -  Department of Child Health, Faculty of Medicine, Universitas Trisakti, Jakarta, Indonesia, Indonesia

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Abstract

Background: An umbilical granuloma is a common benign condition in neonates characterized by the overgrowth of granulation tissue at the base of the umbilicus following umbilical cord detachment. While the standard treatment involves the use of silver nitrate, with its associated risks and need for clinical visits, alternative treatments such as the application of sodium chloride (NaCl) capsules have gained attention for their efficacy, safety, and cost-effectiveness in home settings. Case Presentation: Herein, we present the case of a 3-week-old female infant diagnosed with an umbilical granuloma post umbilical cord detachment. The management involved the application of a 0.5 gram NaCl capsule directly to the granuloma, covered with sterile gauze, and repeated over several days. This approach resulted in a significant reduction in granuloma size and total resolution within two days, without the complications or irritation sometimes associated with silver nitrate. Parents reported ease of administration at home and high satisfaction levels due to the treatment's effectiveness and minimal need for healthcare visits. Conclusion: The use of a 0.5-gram NaCl capsule offers a valid and effective home-based treatment alternative for umbilical granuloma. It provides a practical option, especially where access to silver nitrate is limited, with the added benefits of ease of use and reduced medical costs. With proper parental education and adherence to the treatment protocol, NaCl can serve as a first-line or alternative therapy. Further large-scale studies are recommended to verify long-term effects and potential complications. 

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Keywords: Neonates, Sodium Chloride, Treatment, Umbilical Granuloma, Umbilical Cord

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  1. Muniraman H, Sardesai T, Sardesai S. Disorders of the Umbilical Cord. Pediatr Rev [Internet]. 2018 Jul 1;39(7):332–41. Available from: https://doi.org/10.1542/pir.2017-0202
  2. Nagar H. Umbilical granuloma: a new approach to an old problem. Pediatr Surg Int [Internet]. 2001;17(7):513–4. Available from: https://doi.org/10.1007/s003830100584
  3. Ogawa C, Sato Y, Suzuki C, Mano A, Tashiro A, Niwa T, et al. Treatment with silver nitrate versus topical steroid treatment for umbilical granuloma: A non-inferiority randomized control trial. PLoS One [Internet]. 2018 Feb 13;13(2):e0192688-. Available from: https://doi.org/10.1371/journal.pone.0192688
  4. Daruwalla SB, Dhurat RS. A pinch of salt is all it takes! The novel use of table salt for the effective treatment of pyogenic granuloma. J Am Acad Dermatol [Internet]. 2020 Aug 1;83(2):e107–8. Available from: https://doi.org/10.1016/j.jaad.2019.12.013
  5. Haftu H, Gebremichael TG, Kebedom AG. Salt Treatment for Umbilical Granuloma – An Effective, Cheap, and Available Alternative Treatment Option: Case Report. Pediatric Health Med Ther. 2020;11:393-397 https://doi.org/10.2147/PHMT.S269114
  6. Hossain AKMZ, Hasan GZ, Islam KMD. Therapeutic Effect of Common Salt (Table/ Cooking Salt) on Umbilical Granuloma in Infants. Bangladesh Journal of Child Health [Internet]. 2012 Apr 16;34(3):99–102. Available from: https://www.banglajol.info/index.php/BJCH/article/view/10360
  7. Karaguzel G. Umbilical Granuloma: Modern Understanding of Etiopathogenesis, Diagnosis, and Management. J Pediatr Neonatal Care. 2016 Mar 1;4
  8. Jois R, Rao S. Management of umbilical granuloma in infants: A systematic review of randomised controlled trials. Australian Journal for General Practitioners [Internet]. 2021 Jul 27;50:589–94. Available from: https://www1.racgp.org.au/ajgp/2021/august/management-of-umbilical-granuloma-in-infants
  9. Singh A, Naranje K, Pandita A, Upadhyaya VD, Kumar B,, Upadhyaya AD. Is application of salt for 3 days locally is sufficient to treat umbilical granuloma?. African journal of paediatric surgery : AJPS. 2021;18(3):160–3
  10. Haftu H, Bitew H, Gebrekidan A,, Gebrearegay H. The Outcome of Salt Treatment for Umbilical Granuloma: A Systematic Review. Patient Prefer Adherence. 2022;14:2085–92

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