DOI: https://doi.org/10.14710/dmj.v13i3.42958

The Relationship of Risk Factors on Quality of Life of Laryngeal Carcinoma Patients after Chemoradiation at Kariadi General Hospital

*Albert Juneson  -  Faculty of Medicine, Diponegoro University, Jl. Prof. Sudarto, SH, Tembalang, Semarang, Indonesia 50275, Indonesia, Indonesia
Willy Yusmawan  -  Department of Otorhinolaryngology-Head & Neck Surgery, Faculty of Medicine, Diponegoro University, Semarang, Indonesia, Indonesia
Kanti Yunika  -  Department of Otorhinolaryngology-Head & Neck Surgery, Faculty of Medicine, Diponegoro University, Semarang, Indonesia, Indonesia
RR Lydia Purna Widyastuti Setjadiningrat Kuntjoro  -  Department of Radiology, Faculty of Medicine, Diponegoro University, Semarang, Indonesia, Indonesia

Citation Format:
Abstract

Background: Laryngeal carcinoma is a carcinoma that forms in the tissue of the larynx. The cause of laryngeal carcinoma is not known with certainty, but many risk factors can cause laryngeal carcinomas, such as a history of smoking, alcohol consumption, gender, age, and exposure environment. The quality of life of patients with laryngeal carcinoma after chemoradiation can be influenced by several things, including several risk factors for laryngeal carcinoma. Objective: The purpose of this study was to assess the association of risk factors with the quality of life of laryngeal carcinoma patients after chemoradiation at Kariadi General Hospital. Methods: This study is a cross-sectional study with samples of laryngeal carcinoma patients who have received chemoradiation therapy at Kariadi General Hospital. Sampling was carried out using a consecutive sampling technique using a Univesity of Washington Quality of Life (UW-QoL) questionnaire which was translated into Bahasa. The data from the sampling was then processed using the IBM SPSS Statistics 25.0 application. Results: Overall, the quality of life of laryngeal carcinoma patients after chemoradiation was categorized as “good” quality of life with a mean score of 62. There was no significant relationship (p<0.05) between the quality of life scores and each risk factor for laryngeal carcinoma. Conclusion: There is no significant relationship between risk factors on the quality of life of laryngeal carcinoma patients after chemoradiation at Kariadi General Hospital.

Fulltext View|Download
Keywords: chemoradiation, laryngeal carcinoma, quality of life, risk factors

Article Metrics:

Article Info
Section: Original Articles
Language : EN
Recent articles
The effect combination of black seed (nigella sativa) and glibenclamide on blood glucose levels Correlation between TGF-β Levels and Degree of Wound Healing in Leprosy Ulcer Patients: An Observational Study at dr. Rehatta Regional Hospital Jepara The Relationship of Risk Factors on Quality of Life of Laryngeal Carcinoma Patients after Chemoradiation at Kariadi General Hospital More recent articles
  1. Siegel RL, Miller KD, Jemal A. Cancer statistics, 2016. CA Cancer J Clin. 2016;66(1):7-30. doi: 10.3322/caac.21332
  2. Kemenkes RI. Profil Kesehatan Indonesia 2018 Kemenkes RI.; 2019
  3. Wiliayanto O. Insidensi Kanker Kepala Leher Berdasarkan Diagnosis Patologi Anatomi di RS Kariadi Semarang Periode 1 Januari 2001 - 31 Desember 2005. Fak Kedokt Univ Diponegoro. Published online 2006
  4. Bosetti C, Gallus S, Franceschi S, et al. Cancer of the larynx in non-smoking alcohol drinkers and in non-drinking tobacco smokers. Br J Cancer. Published online 2002. doi: 10.1038/sj.bjc.6600469
  5. Steuer CE, El-Deiry M, Parks JR, Higgins KA, Saba NF. An update on larynx cancer. CA Cancer J Clin. Published online 2017. doi: 10.3322/caac.21386
  6. Rahman S, Budiman BJ, Swanda D. Diagnosis dan Penatalaksanaan Karsinoma Sel Skuamosa Glotis Stadium Dini. J Kesehat Andalas. Published online 2016
  7. Williamson JS, Ingrams D, Jones H. Quality of life after treatment of laryngeal carcinoma: A single centre cross-sectional study. Ann R Coll Surg Engl. 2011;93(8):591-595. doi: 10.1308/147870811X13137608455253
  8. Al-Mamgani A, van Rooij PH, Woutersen DP, et al. Radiotherapy for T1-2N0 glottic cancer: A multivariate analysis of predictive factors for the long-term outcome in 1050 patients and a prospective assessment of quality of life and voice handicap index in a subset of 233 patients. Clin Otolaryngol. 2013;38(4):306-312. doi: 10.1111/coa.12139
  9. Kolator M, Mikuła B, Maciejczyk A, Zatoński T. Polish validation of the University of Washington “quality of life” questionnaire in patients with cancer of the larynx. Br J Oral Maxillofac Surg. 2019;57(3):226-231. doi: 10.1016/j.bjoms.2018.12.013
  10. Meleca RJ, Dworkin JP, Kewson DT, Stachler RJ, Hill SL. Functional outcomes following nonsurgical treatment for advanced-stage laryngeal carcinoma. Laryngoscope. 2003;113(4):720-728. doi: 10.1097/00005537-200304000-00025
  11. Odwyer MC, Meixner K, Albiac LC, et al. Health-related quality of life for people with acute and chronic illnesses during the covid-19 pandemic. J Am Board Fam Med. 2021;34(3):509-521. doi: 10.3122/JABFM.2021.03.200593
  12. Aarstad HJ, Østhus AA, Aarstad HH, Lybak S, Aarstad AKH. EORTC Quality of Life Questionnaire Head and Neck (H&N)-35 scores from H&N squamous cell carcinoma patients obtained at diagnosis and at 6, 9 and 12 months following diagnosis predict 10-year overall survival. Eur Arch Oto-Rhino-Laryngology. Published online 2019. doi: 10.1007/s00405-019-05630-2
  13. Duffy SA, Terrell JE, Valenstein M, Ronis DL, Copeland LA, Connors M. Effect of smoking, alcohol, and depression on the quality of life of head and neck cancer patients. Gen Hosp Psychiatry. 2002;24(3):140-147. doi: 10.1016/S0163-8343(02)00180-9
  14. Danker H, Keszte J, Singer S, et al. Alcohol consumption after laryngectomy. Clin Otolaryngol. 2011;36(4):336-344. doi: 10.1111/j.1749-4486.2011.02355.x
  15. Tan S, Duong Dinh TA, Westhofen M. Evaluation of gender-specific aspects in quality-of-life in patients with larynx carcinoma. Acta Otolaryngol. Published online 2016. doi: 10.1080/00016489.2016.1211319
  16. Lee MT, Gibson S, Hilari K. Gender differences in health-related quality of life following total laryngectomy. Int J Lang Commun Disord. 2010;45(3):287-294. doi: 10.3109/13682820902994218
  17. Leoncini E, Ricciardi W, Cadoni G, et al. Adult height and head and neck cancer: A pooled analysis within the INHANCE Consortium. Head Neck. 2014;36(10):1391. doi: 10.1002/HED
  18. Bouvard V, Baan R, Straif K, et al. A review of human carcinogens--Part B: biological agents. Lancet Oncol. Published online 2009. doi: 10.1016/s1470-2045(09)70096-8
  19. Peng W-J, Mi J, Jiang Y-H. Asbestos exposure and laryngeal cancer mortality. Laryngoscope. 2016;126(5):1169-1174. doi: 10.1002/lary.25693

Last update:

No citation recorded.

Last update:

No citation recorded.