Evaluation of the Quantity and Quality of Antibiotic Use in Inpatient Pediatric Urinary Tract Infection (UTI) Patients at RSUD KRMT Wongsonegoro Semarang

Putri Heryalien Gusa; Eva Annisaa'; Intan Rahmania Eka Dini

doi:10.14710/dmj.v13i3.41447

DOI: https://doi.org/10.14710/dmj.v13i3.41447

Evaluation of the Quantity and Quality of Antibiotic Use in Inpatient Pediatric Urinary Tract Infection (UTI) Patients at RSUD KRMT Wongsonegoro Semarang

Putri Heryalien Gusa - Pharmacy Study Program, Universitas Diponegoro, Jl. Prof. Sudarto, SH, Tembalang, Semarang, Indonesia 50275, Indonesia

*Eva Annisaa'

- Pharmacy Study Program, Universitas Diponegoro, Jl. Prof. Sudarto, SH, Tembalang, Semarang, Indonesia 50275, Indonesia

Intan Rahmania Eka Dini - Pharmacy Study Program, Universitas Diponegoro, Jl. Prof. Sudarto, SH, Tembalang, Semarang, Indonesia 50275, Indonesia

BibTex Citation Data :

@article{dmj41447,
    author = {Putri Heryalien Gusa and Eva Annisaa' and Intan Rahmania Eka Dini},
    title = {Evaluation of the Quantity and Quality of Antibiotic Use in Inpatient Pediatric Urinary Tract Infection (UTI) Patients at RSUD KRMT Wongsonegoro Semarang},
    journal = {Jurnal Kedokteran Diponegoro (Diponegoro Medical Journal)},
  volume = {13},
    number = {3},
    year = {2024},
    keywords = {Antibiotics, Pediatrics, Urinary Tract Infection},
    abstract = {  Background:  Antibiotics are the main drug in the treatment of various infectious diseases. The high use of antibiotics can cause bacterial resistance to antibiotics so it is necessary to evaluate antibiotics both in quantity (amount of antibiotics used) and quality (accuracy of antibiotic use).   Objective:  This study was conducted to determine the quantity and quality of antibiotic use in pediatric urinary tract infection (UTI) patients hospitalized at KRMT Wongsonegoro Hospital Semarang.   Methods:  This study was a retrospective cross-sectional study. The study materials were medical records of pediatric UTI patients who were hospitalized at KRMT Wongsonegoro Hospital Semarang. Analysis was performed qualitatively using the Gyssens method and quantitatively using the ATC/DDD and DU90% methods.   Results:  There were 46 prescriptions from 43 pediatric UTI patients. The most commonly used single antibiotic was ceftriaxone (47.73%). Evaluation of the quantity of antibiotic use obtained the total DDD (Defined Daily Dose) value of pediatric UTI patients in the 2019-2022 period was 40.39 DDD/100 patient-days. Antibiotics that fall into the DU90% segment are ceftriaxone and cefotaxime. Evaluation of the quality of antibiotic use obtained 8 of antibiotic use is appropriate/wise.  Conclusion:  There is still inappropriate antibiotic use in pediatric UTI patients at KRMT Wongsonegoro Hospital in 2019-2022.},
   issn = {2540-8844},   pages = {119--125}  doi = {10.14710/dmj.v13i3.41447},
    url = {https://ejournal3.undip.ac.id/index.php/medico/article/view/41447}
}

Citation Format:

Abstract

Background: Antibiotics are the main drug in the treatment of various infectious diseases. The high use of antibiotics can cause bacterial resistance to antibiotics so it is necessary to evaluate antibiotics both in quantity (amount of antibiotics used) and quality (accuracy of antibiotic use).

Objective: This study was conducted to determine the quantity and quality of antibiotic use in pediatric urinary tract infection (UTI) patients hospitalized at KRMT Wongsonegoro Hospital Semarang.

Methods: This study was a retrospective cross-sectional study. The study materials were medical records of pediatric UTI patients who were hospitalized at KRMT Wongsonegoro Hospital Semarang. Analysis was performed qualitatively using the Gyssens method and quantitatively using the ATC/DDD and DU90% methods.

Results: There were 46 prescriptions from 43 pediatric UTI patients. The most commonly used single antibiotic was ceftriaxone (47.73%). Evaluation of the quantity of antibiotic use obtained the total DDD (Defined Daily Dose) value of pediatric UTI patients in the 2019-2022 period was 40.39 DDD/100 patient-days. Antibiotics that fall into the DU90% segment are ceftriaxone and cefotaxime. Evaluation of the quality of antibiotic use obtained 8 of antibiotic use is appropriate/wise.

Conclusion: There is still inappropriate antibiotic use in pediatric UTI patients at KRMT Wongsonegoro Hospital in 2019-2022.

Note: This article has supplementary file(s).

Fulltext View|Download | Ethical Clearance

ETHICAL CLEARENCE “EVALUASI KUANTITAS DAN KUALITAS PENGGUNAAN ANTIBIOTIK PADA PASIEN INFEKSI SALURAN KEMIH (ISK) PEDIATRI RAWAT INAP DI RSD K.R.M.T WONGSONEGORO SEMARANG”

Subject
Type	Ethical Clearance
	Download (551KB) Indexing metadata

Keywords: Antibiotics, Pediatrics, Urinary Tract Infection

Article Metrics:

Article Info

Section: Original Articles

Language : EN

In Vol 13, No 3 (2024): JURNAL KEDOKTERAN DIPONEGORO (DIPONEGORO MEDICAL JOURNAL)

Recent articles

The Effect of Moringa Leaves Extract on Sperm Motility in Male Mice Exposed to Electromagnetic Radiation of Mobile Phone Correlation between Degree of Leprosy Disability and Serum IL-6 Levels in Patients with Leprosy Reactions: An Observational Study at the Donorojo Jepara Leprosy Hospital Center The Relationship of Risk Factors on Quality of Life of Laryngeal Carcinoma Patients after Chemoradiation at Kariadi General Hospital More recent articles

Smeltzer SC dan Bare BG. Textbook of Medical-Surgical Nursing, 8th edition. Philadelphia: Lippincott Williams & Wilkins; 2008
WHO. Pelayanan Kesehatan Anak di Rumah Sakit. Jakarta: World Health Organization; 2011
Departemen Kesehatan Republik Indonesia. Waspada Infeksi Saluran Kemih. Jakarta: Departemen Kesehatan Republik Indonesia; 2014
Subandiyah K. Gangguan Berkemih pada Anak. Surabaya: Airlangga University Press; 2015
PERMENKES RI. Pedoman Umum Penggunaan Antibiotik. Jakarta: Kementrian Kesehatan RI; 2011
Desrini S. Resistensi Antibiotik, Akankah Dapat Dikendalikan?. JKKI: Jurnal Kedokteran dan Kesehatan Indonesia. 2015:1-2
Mazzariol A, Bazaj A, Cornaglia G. Multi-drug-resistant Gram-negative bacteria causing urinary tract infections: a review. Journal of Chemotherapy. 2017;29(sup1):2-9
Harahap NI. Penggunaan Antibiotik pada Penyakit Infeksi Saluran Kemih di RSU Datu Beru Takengon. JIFI (Jurnal Ilmiah Farmasi Imelda). 2019;2(2):69-74
Kusumawardani LH, Saputri AA. Gambaran Pengetahuan, Sikap dan Keterampilan Perilaku Hidup Bersih Sehat (PHBS) pada Anak Usia Sekolah. Jurnal Ilmiah Ilmu Keperawatan Indonesia. 2020 Jun 10;10(02):82-9
Polito C. Association of Medical School Pediatric Department Chairs. Inc. Unilateral Vesico Ureteric Reflux: Low Pevalence of Contralateral Renal Damage, Pediatrics: 2011
Purnomo B. Dasar-Dasar Urologi. Malang: Penerbit Sagung Setyo; 2011
Grabe M, Bartoletti R, Johansen Bjerklund T E, et al. Guideline in Urological Infection. European Association of Urology; 2015
Ikatan Ahli Urologi Indonesia (IAUI). Tata Laksana Infeksi Saluran Kemih dan Genitalia Pria 2020. Jakarta: Ikatan Ahli Urologi Indonesia; 2021
Ikatan Dokter Anak Indonesia. Konsensus Infeksi Saluran Kemih pada Anak Jakarta: Badan Penerbit IDAI; 2011
Radmayr C, Bogaert G, Burgu B, Dogan HS, Nijman JM, Quaedackers J. EAU Guidelines on Paediatric Urology. European Association of Urology; 2023
Yuniarti E, Rani AM, Handayani EW. Evaluasi Penggunaan Antibiotika Pada Infeksi Saluran Kemih Dengan Metode ATC/DDD DI RSUD Dr. Soedirman Kebumen. Jurnal Farmasi Klinik dan Sains. 2021 Dec 5;1(1):6-10
WHO Collaborating Centre for Drug Statistics Methodology. Guidelines for ATC Classification and DDD Assignment 2020. Norway: WHO Collaborating Centre for Drug Statistics Methodology; 2020
Rachmawati S, Masito DK, Rachmawati E. Evaluasi Penggunaan Antibiotik Pada Pasien Anak Rawat Inap di RSD Dr. Soebandi Jember. J Farm Galen (Galenika J Pharmacy). 2020;6(2)
Novard MF, Suharti N, Rasyid R. Gambaran Bakteri Penyebab Infeksi pada Anak Berdasarkan Jenis Spesimen dan Pola Resistensinya di Laboratorium RSUP Dr. M. Djamil Padang tahun 2014-2016. Jurnal Kesehatan Andalas. 2019;8(2S):26-32
Adhitama W, Puspitasari I, Laksanawati IS. Evaluasi Luaran Klinis Terapi Antibiotika pada Pasien Anak Rawat Inap Dengan Infeksi Saluran Kemih di RSUP Dr. Sardjito Yogyakarta. Majalah Farmaseutik. 2021;17(2):166-74
Aberg, JA. Lacy, C. Amstrong, L. Goldman, M. and Lance, LL. Drug Information Handbook 17th Edition. American Pharmacist Association; 2009
Robinson JL, Finlay JC, Lang ME, Bortolussi R, Canadian Paediatric Society, Community Paediatrics Committee, Infectious Diseases and Immunization Committee. Urinary tract infection in infants and children: Diagnosis and management. Paediatrics & child health. 2014 Jun 13;19(6):315-9
Cipolle RJ, Strand LM, Morley PC. Pharmaceutical Care Practice. New York: Mc Graw Hill Company; 1998
Santosa YSA, Tarmono AR, Daryanto GWKDB, Wahyudi I. Urologi Anak (Pediatric Urology) di Indonesia. Ikatan Ahli Urologi Indonesia; 2016
Priyanto. Farmakoterapi dan Terminologi Medis. Depok: Lembaga Studi dan Konsultasi Farmakologi; 2009
Kemenkes. Pedoman Pelayanan Kefarmasian untuk Terapi Antibiotik. Jakarta: Kementrian kesehatan RI; 2011

Last update:

No citation recorded.

Last update:

No citation recorded.

Authors who publish with this journal agree to the following terms: - Authors retain copyright and grant the journal right of first publication with the work simultaneously licensed under a Creative Commons Attribution-NonCommercial-ShareAlike 4.0 International License (CC-BY-NC-SA) that allows others to share the work with an acknowledgment of the work’s authorship and initial publication in this journal. - Authors are able to enter into separate, additional contractual arrangements for the non-exclusive distribution of the journal’s published version of the work (e.g., post it to an institutional repository or publish it in a book), with an acknowledgment of its initial publication in this journal. - Authors are permitted and encouraged to post their work online (e.g., in institutional repositories or on their website) prior to and during the submission process, as it can lead to productive exchanges, as well as earlier and greater citation of published work (See The Effect of Open Access).