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Evaluation of the Quantity and Quality of Antibiotic Use in Inpatient Pediatric Urinary Tract Infection (UTI) Patients at RSUD KRMT Wongsonegoro Semarang

Putri Heryalien Gusa  -  Pharmacy Study Program, Universitas Diponegoro, Jl. Prof. Sudarto, SH, Tembalang, Semarang, Indonesia 50275, Indonesia
*Eva Annisaa' orcid  -  Pharmacy Study Program, Universitas Diponegoro, Jl. Prof. Sudarto, SH, Tembalang, Semarang, Indonesia 50275, Indonesia
Intan Rahmania Eka Dini  -  Pharmacy Study Program, Universitas Diponegoro, Jl. Prof. Sudarto, SH, Tembalang, Semarang, Indonesia 50275, Indonesia

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Abstract

Background: Antibiotics are the main drug in the treatment of various infectious diseases. The high use of antibiotics can cause bacterial resistance to antibiotics so it is necessary to evaluate antibiotics both in quantity (amount of antibiotics used) and quality (accuracy of antibiotic use).

Objective: This study was conducted to determine the quantity and quality of antibiotic use in pediatric urinary tract infection (UTI) patients hospitalized at KRMT Wongsonegoro Hospital Semarang.

Methods: This study was a retrospective cross-sectional study. The study materials were medical records of pediatric UTI patients who were hospitalized at KRMT Wongsonegoro Hospital Semarang. Analysis was performed qualitatively using the Gyssens method and quantitatively using the ATC/DDD and DU90% methods.

Results: There were 46 prescriptions from 43 pediatric UTI patients. The most commonly used single antibiotic was ceftriaxone (47.73%). Evaluation of the quantity of antibiotic use obtained the total DDD (Defined Daily Dose) value of pediatric UTI patients in the 2019-2022 period was 40.39 DDD/100 patient-days. Antibiotics that fall into the DU90% segment are ceftriaxone and cefotaxime. Evaluation of the quality of antibiotic use obtained 8 of antibiotic use is appropriate/wise.

Conclusion: There is still inappropriate antibiotic use in pediatric UTI patients at KRMT Wongsonegoro Hospital in 2019-2022.

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ETHICAL CLEARENCE “EVALUASI KUANTITAS DAN KUALITAS PENGGUNAAN ANTIBIOTIK PADA PASIEN INFEKSI SALURAN KEMIH (ISK) PEDIATRI RAWAT INAP DI RSD K.R.M.T WONGSONEGORO SEMARANG”
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Keywords: Antibiotics, Pediatrics, Urinary Tract Infection

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