skip to main content

Post COVID-19 Immunization Herpes Zoster Reactivation In Asia : A Literature Review

*Nurul Nisa Ulfa  -  Faculty of medecine, Diponegoro University, Indonesia, Indonesia
Danisa Diandra Safarina  -  Faculty of Medicine, Diponegoro University, Indonesia, Indonesia
Puguh Riyanto  -  Department of Dermatovenereology, Faculty of Medicine, Diponegoro University, Indonesia, Indonesia

Citation Format:
Abstract

Background: The COVID-19 vaccine that targets viral mRNA has been created and can be used as an effort to end the COVID-19 pandemic that has hit the world since 2020. The COVID-19 vaccine currently being developed has proven its effectiveness and safety in the general adult population.

Objective: To identify reactivation of Herpes Zoster virus post COVID-19 vaccine.

Methods: This article review discusses four case reports of Herpes Zoster following the COVID-19 immunization in Asia which were obtained from various sources such as Pubmed Medline Embase.

Results: The mRNA-type vaccine is associated with skin manifestations with an increased incidence (14.4%) of Herpes Zoster which was observed around 6-8 days after administration of the first dose of vaccine (BNT162b2 vaccine) and 1.5% after administration of the mRNA- 1273 which occurred in the Asian Oceanian race. COVID-19 vaccine substances such as polyethylene glycol (PEG), the polysorbate present in mRNA vaccines, and polysorbate 80 are suspected causing an allergic reactions.

Conclusion: Health workers must be careful in administering the COVID-19 vaccine, especially to individuals who have risk factors that can decrease their immune system so it can cause reactivation of Herpes Zoster.

 

 

 

Fulltext View|Download
Keywords: Covid-19; Herpes Zoster;Covid-19 Vaccine;Reactivation of Herpes Zoster Virus Post Covid-19 Vaccine

Article Metrics:

  1. Shereen MA, Khan S, Kazmi A, Bashir N, R. S. COVID-19 infection: Origin, transmission, and characteristics of human coronaviruses. 2020;24:91-8. DOI: 10.1016/j.jare.2020.03.005
  2. CSIS. National Responses to COVID-19 in Southeast Asia. Washington DC: 2022
  3. Barouch DH. Covid-19 Vaccines — Immunity, Variants, Boosters. N Engl J Med. 2022;378(11):1011-20. Available from: https://www.nejm.org/doi/full/10.56/NEJMra2206573
  4. Watson OJ, Barnsley G, Toor J, Hogan AB, Winskill P, Ghani AC. Global impact of the first year of COVID-19 vaccination: a mathematical modelling study. Lancet Infect Dis [Internet]. 2022;22(9):1293-302
  5. WHO. Side Effects of COVID-19 Vaccines [Internet]. 2021. Available from: https://www.who.int/news-room/feature-stories/detail/side-effects-of-covid-19-vaccines
  6. Eden David BA ALM. Herpes Zoster Following COVID-19 Vaccination. J Drugs Dermatology [Internet]. 2021;20(8): . Available from: https://jddonline.com/articles/herpes-zoster-following-covid-19-vaccination-S1545961621P0898X/
  7. Shengli Xia KD. Effect Of An Inactivated Vaccine Against SARS-COV-2 On Safety and Immunogenicity Outcomes. 2020;324(10):1-10
  8. Lotfi M, Hamblin MR, N. R. The COVID-19 resource centre is hosted on Elsevier Connect , the company ’ s public news and information. Clin Chim Acta [Internet]. 2020;508((January)):254-66. Available from: www.elsevier.com/locate/cca Review
  9. Préta LH, Contejean A, Salvo F, Treluyer JM, Charlier C, Chouchana L. Association study between herpes zoster reporting and mRNA COVID-19 vaccines (BNT162b2 and mRNA-1273). Br J Clin Pharmacol [Internet]. 2022;88(7):3529-34. Available from: https://bpspubs.onlinelibrary.wiley.com/doi/10.1111/bcp.15280
  10. You I-C, Ahn M, Cho N-C. A Case Report of Herpes Zoster Opthalmicus and Meningitis After COVID-19 Vaccination. J Korean Med Sci [Internet]. 2022;37. Available from: https://jkms.org/pdf/10.3346/jkms.2022.37.e165
  11. Shah S, Baral B, Chamlagain R, Murarka H, Raj Adhikari Y, B. SP. Reactivation of herpes zoster after vaccination with an inactivated vaccine: A case report from Nepal. Clin Case Reports [Internet]. 2021;9(12):1-3. Available from: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8650754/pdf/CCR3-9-e05188.pdf
  12. BM Munasinghe, UPM Fernando, DS. MM. Reactivation of Varicella-Zoster Virus Following MRNA COVID-19 Vaccination In A Patient With Moderately Differentiated Adenocarcinoma Of Rectum : A Case Report. 2022;10:1-4. Available from: https://pdfs.semanticscholar.org/5c4f/680a62932bcde4e4c3df17e16d7eb710de.pdf?_ga=2.264491148.2079252552.1667980922-876371522
  13. Aksu, Saliha Busra GZO. A Rare Case of Shingles After COVID-19 Vaccine: Is It a Possible Adverse Effect? Clin Exp Vaccine Res. 2021
  14. Nawaf Almutairi, Abdulrahman N, SA. MA. Herpes zoster in The Era of COVID 19: A Prospective Observational Study to Probe The Association of Herpes Zoster with COVID 19 Infection and Vaccination. 2022
  15. Dworkin RH, Johnson RW, Breuer J, Gnann JW, Levin MJ, Backonja M ea. Recommendations for the management of herpes zoster. Clin Infect Dis [Internet]. 2007;44(1):1-26. Available from: https://academic.oup.com/cid/article/44/Supplement_1/S1/334966?login=true
  16. McMahon DE AE, Rosenbach M, Lipoff JB, Moustafa D, Tyagi A, et al. Cutaneous reactions reported after Moderna and Pfizer COVID-19 vaccination: A registry-based study of 414 cases. J Am Acad Dermatol. 2021;85(1):46-55
  17. West JA GS, Damania B. Toll-like receptor sensing of human herpesvirus infection. Front Cell Infect Microbiol [Internet]. 2012;2(October):122. Available from: https://www.frontiersin.org/articles/10.3389/fcimb.2012.00122/full
  18. Anderson EJ RN, Widge AT, Jackson LA, Roberts PC, Makhene M, et al. Safety and Immunogenicity of SARS-CoV-2 mRNA-1273 Vaccine in Older Adults. N Engl J Med [Internet]. 2020;383(25):2427-38. Available from: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7556339/pdf/NEJMoa2028436.pdf
  19. Psichogiou M KA, Poulakou G, Antoniadou A, Kotanidou A, Degiannis D, et al. . Comparative immunogenicity of BNT162b2 mRNA vaccine with natural SARS-CoV-2 infection. Vaccines [Internet]. 2021;9(9):1-13. Available from: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7556339/pdf/NEJMoa2028436.pdf
  20. Psichogiou M SM, Mikos N, Hatzakis A. Reactivation of varicella zoster virus after vaccination for sars-cov-2. Vaccines. 2021;9(6):1-8
  21. WHO. The COVID-19 Vaccine Tracker and Landscape Compiles Detailed Information Of Each COVID-19 Vaccine Candidate In Development By Closely Monitoring Their Progress Through The Pipeline. 2022. Available from: https://www.who.int/publications/m/item/draft-landscape-of-covid-19-candidate-vaccines
  22. Lucie Renoud CK, Pharm BR. Association of Facial Paralysis With mRNA COVID-19 Vaccines. 2021;181(9):1243-5. Available from: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8080152/
  23. Bogdanov G BI, Kazandjieva J, Tsankov N. Cutaneous adverse effects of the available COVID-19 vaccines: Effects of COVID-19 vaccines. Clin Dermatol [Internet]. 2021;39(3):523-32. Available from: https://doi.org/10.1016/j.clindermatol.2021.04.001
  24. G.Kounis N, Loanna Koniari C de G. Effect of an Inactivated Vaccine Against SARS-CoV-2 on Safety and Immunogenicity Outcomes. Vaccines. 2021;9(3)
  25. Shauna M Rice SDFN. The Art of Prevention: COVID-19 Vaccine Preparedness For the Dermatologist. Dermatology. 2021;7(2)

Last update:

No citation recorded.

Last update:

No citation recorded.