DOI: https://doi.org/10.14710/jnc.v13i3.42821

PERAN SENYAWA BIOAKTIF RUMPUT LAUT TERHADAP RESPON GLUKOSA DARAH PADA INDIVIDU OBESITAS: LITERATUR REVIEW

Departemen Ilmu Gizi, Fakultas Kedokteran, Universitas Diponegoro, Jawa Tengah, Indonesia

Received: 3 Mar 2024; Revised: 17 Jul 2024; Accepted: 19 Jul 2024; Available online: 31 Jul 2024; Published: 31 Jul 2024.

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Abstract

ABSTRACT

Obesity is considered as a risk factor for insulin resistance and hyperglycemia. Strategies for glycemic control are necessary in order to prevent obese individuals from developing diabetes mellitus. Over the last few years, research regarding natural products obtained from seaweed has increased since it contains various bioactive compounds; such as, polysaccharides, polyphenols, carotenoids, fucoxanthin and others. These compounds appear to have various biological effects which are beneficial to health; such as, antioxidant, anti-inflammatory, antimicrobial and anti-diabetic activities. In addition, the low energy content of seaweed and various bioactive compounds can prevent diabetes through various mechanisms. This narrative review provides summary of the various bioactive compounds contained in seaweed and provides a summary regarding the mechanisms of seaweed bioactive compounds on blood glucose responses in obese individuals.

Keywords: Seaweed; bioactive compounds; blood glucose; obesity

 

                                                                          ABSTRAK

Obesitas merupakan faktor risiko terjadinya resistensi insulin dan hiperglikemia. Kontrol glikemik sangat penting untuk menjaga individu obesitas agar tidak sampai pada kondisi diabetes mellitus, sehingga diperlukan strategi untuk mengontrol glikemik. Selama beberapa tahun terakhir, penelitian terkait produk alami yang diperoleh dari rumput laut semakin meningkat karena mengandung berbagai senyawa bioaktif seperti polisakarida, polifenol, karotenoid, fukosantin dan lainnya. Senyawa tersebut tampaknya memiliki berbagai efek biologis yang bermanfaat bagi kesehatan seperti aktivitas antioksidan, antiinflamasi, antimikroba, dan antidiabetes. Selain itu, kandungan energi yang rendah pada rumput laut dan berbagai senyawa bioaktif dapat mencegah diabetes melalui berbagai mekanisme. Tinjauan naratif ini merangkum berbagai kandungan senyawa bioaktif rumput laut dan memberikan ringkasan terkait mekanisme senyawa biaktif rumput laut terhadap respon glukosa darah pada individu obesitas.

Kata Kunci: Rumput laut; senyawa bioaktif; glukosa darah; obesitas


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Keywords: Rumput laut; senyawa bioaktif; glukosa darah; obesitas

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