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HUBUNGAN DEPRESI DAN MALNUTRISI PADA LANJUT USIA: STUDI LITERATUR

Rumah Sakit TK.II Kartika Husada, Kubu Raya, Kalimantan Barat,, Indonesia

Received: 7 Sep 2023; Revised: 5 Sep 2024; Accepted: 19 Sep 2024; Available online: 22 Oct 2024; Published: 22 Oct 2024.

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Abstract

ABSTRACT

Background: Elderly are susceptible to disease and experience a decrease in body function, and their number is increasing both globally and nationally. Maintaining the elderly in optimal conditions is very important, but malnutrition prevalence in the elderly is high. Malnutrition can be caused by various factors, one of which is depression.

Objectives: The aim of this literature study was to review the latest research related to depression with malnutrition in the elderly

Methods: The search for 2011 – 2021 English-language articles were carried out on the PubMed, SpringerLink, ScienceDirect, DOAJ, and ResearchGate databases using the keyword Depression AND (Nutritional Status OR Malnutrition) AND Elderly and it was found that 13 articles were selected based on inclusion criteria, including articles with elderly subjects aged ≥60 years in the community, a minimum sample of 50 respondents, a cross-sectional or prospective cohort study, analyzed the relationship between variables, and data collection using valid instruments by a trained people.

Results: Depression is independently significantly related to nutritional status in the elderly. Depression can reduce appetite. Reduced appetite will cause decrease in food intake and cause a decrease in nutritional status. Depression can also affect food’s choices so that elder chose low nutrtionous food and nutrition requirement can not be reached. Malnutrition can also affect depression due to the lack of certain nutrients that affect neurotransmitter in the brain. The difference in the sample’s characteristics can affect the relationship of the variables.

Conclusion: The existence of a relationship between the two variables found in most of the studies indicates that depression is an important factor that can lead to malnutrition in the elderly. However manultrition is a complex problem that need interdisciplinary approach.

Keywords: Elderly; Depression; Malnutrition, Nutritional status

 

ABSTRAK

Latar belakang: Lansia rentan terhadap penyakit, mengalami penurunan fungsi tubuh dan jumlahnya makin meningkat baik secara global maupun secara nasional. Menjaga kondisi lansia dalam keadaan optimal sangat penting, namun prevalensi lansia dengan malnutrisi cukup tinggi. Malnutrisi dapat disebabkan oleh berbagai faktor, salah satunya depresi.

Tujuan: Mengkaji penelitian terkini terkait hubungan depresi dan malnutrisi pada lansia

Metode: Pencarian artikel berbahasa Inggris tahun 2013 - 2023 dilakukan pada database PubMed, SpringerLink, ScienceDirect, DOAJ, dan ResearchGate dengan penggunaan kata kunci Depression AND (Nutritional Status OR Malnutrition) AND Elderly dan ditemukan sebanyak 13 artikel terpilih yang telah disesuaikan dengan kriteria inklusi, yaitu artikel dengan subjek lansia berusia ≥ 60tahun di komunitas, sampel minimal 50 responden, desain cross sectional atau cohort prospective, menganalisis hubungan antar variabel, dan pengambilan data dengan instrumen yang valid oleh orang yang terlatih.

Hasil: Depresi secara independen berhubungan signifikan dengan status gizi pada lansia. Depresi dapat mengurangi selera makan. Penurunan pada selera makan akan menurunkan asupan makan, sehingga menyebabkan penurunan status gizi. Depresi juga dapat memengaruhi dalam pemilihan jenis makanan, sehingga lansia memilih makanan yang kurang bernutrisi, akibatnya kebutuhan gizi tidak dapat terpenuhi. Malnutrisi juga dapat memengaruhi kondisi depresi akibat kekurangan zat gizi tertentu yang memengaruhi neurotransmiter di otak. Perbedaan karakteristik sampel dapat memengaruhi keterkaitan variabel.

Simpulan: Depresi merupakan dapat mendorong terjadinya malnutrisi pada lansia. Walaupun demikian malnutrisi merupakan suatu permasalahan yang kompleks, oleh karena itu membutuhkan pendekatan secara interdisipliner.

Kata Kunci : Depresi; Lansia; Malnutrisi; Status Gizi

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Keywords: Depresi; Lansia; Malnutrisi; Status Gizi

Article Metrics:

  1. Kemenkes RI. Indonesia Masuki Periode Aging Population. Pusat Data dan Informasi Kementerian Kesehatan RI Jakarta: Kementerian Kesehatan RI. 2019;
  2. BPS. Satistik Penduduk Lanjut Usia 2019. 2019
  3. Sunarti S, Fatma S, Putri F, Oktavia N, Miamaretta A SS. MalnutritionProblem in Older Adults : Risk Factors,Consequences, and Therapeutic Approach. Klinik dan Riset Kesehatan. 2023;2(3):350–64. DOI 10.11594/jk-risk.02.3.5
  4. Krishnamoorthy Y, Vijayageetha M, Kumar SG, Rajaa S RT. Prevalence of malnutrition and its associated factors among elderly population in rural Puducherry using mini nutritional assessment questionnaire. J Family Med Prim Care. 2017;6(2):169–70. DOI 10.4103/jfmpc.jfmpcPMID29026777
  5. Pusdatin. Situasi Lanjut Usia (Lansia) di Indonesia. Retrieved. 2016;10(10):2020
  6. Putra IGY, Febianingsih NPE. Gambaran status gizi pada lanjut usia di panti Wredha wana sraya Denpasar. Bali Health Published Journal. 2019 Jun 1;1(1):10–7. DOI 10.47859/bhpj.v1i1.98
  7. LeMay LG, Vander AJ, Kluger MJ. The effects of psychological stress on plasma interleukin-6 activity in rats. Physiol Behav. 1990 May;47(5):957–61. DOI 10.1016/0031-9384(90)90024-X
  8. Baxter LC. Appetite changes in depression. American Journal of Psychiatry [Internet]. 2016 Apr 1;173(4):317–8. DOI 10.1176/appi.ajp.2016.16010010
  9. Prabhaswari L, Putu Ariastuti NL. Gambaran kejadian depresi pada lanjut usia di wilayah kerja Puskesmas Petang I Kabupaten Badung Bali 2015. Intisari Sains Medis. 2016 Dec 15;7(1):47–52. DOI 10.15562/ism.v7i1.100
  10. Chen CT, Tung HH, Chen YC, Lee HF, Wang CJ, Lin WH. Depressive symptoms and nutritional status in the frail older adults. Arch Gerontol Geriatr. 2019;83:96–100. DOI 10.1016/j.archger.2019.03.023PMID30991156
  11. Yoshimura K, Yamada M, Kajiwara Y, Nishiguchi S, Aoyama T. Relationship between depression and risk of malnutrition among community-dwelling young-old and old-old elderly people. Aging Ment Health. 2013;17(4):456–60. DOI 10.1080/13607863.2012.743961PMID23176659
  12. Suzana S, Boon PC, Chan PP, Normah CD. Malnutrition risk and its association with appetite, functional and psychosocial status among elderly Malays in an agricultural settlement. Malays J Nutr. 2013 Apr;19(1):65–75. PMID24800385
  13. El Zoghbi M, Boulos C, Awada S, Rachidi S, Al-Hajje A, Bawab W, et al. Prevalence of malnutrition and its correlates in older adults living in long stay institutions situated in Beirut, Lebanon. J Res Health Sci. 2014;14(1):11–7. PMID24402844
  14. Gruber MT, Witte OW, Grosskreutz J, Prell T. Association between malnutrition, clinical parameters and health-related quality of life in elderly hospitalized patients with Parkinson’s disease: A cross-sectional study. PLoS One. 2020;15(5). DOI 10.1371/journal.pone.0232764
  15. Salis F, Loddo S, Zanda F, Peralta MM, Serchisu L, Mandas A. Comprehensive Geriatric Assessment: Application and correlations in a real-life cross-sectional study. Front Med (Lausanne). 2022;9:984046. DOI 10.3389/fmed.2022.984046PMID36177326
  16. Gündüz E, Eskin F, Gündüz M, Bentli R, Zengin Y, Dursun R, et al. Malnutrition in Community-Dwelling Elderly in Turkey: A Multicenter, Cross-Sectional Study. Med Sci Monit. 2015 Sep;21:2750–6. DOI 10.12659/MSM.893894PMID26371941
  17. Sato R, Sawaya Y, Shiba T, Hirose T, Sato M, Ishizaka M. Malnutrition is associated with depression in Japanese older adults requiring long-term care or support. J Phys Ther Sci. 2021 Aug;33(8):585–90. DOI 10.1589/jpts.33.585PMID34393368
  18. Saha S, Basu A, Ghosh S, Saha AK, Banerjee U. Assessment of Nutritional Risk and Its Associated Factors among Elderly Women of Old Age Homes of South Suburban Kolkata, West Bengal, India. J Clin Diagn Res. 2014 Feb;8(2):118–20. DOI 10.7860/JCDR/2014/8321.4024PMID24701499
  19. Mokhber N, Majdi M, Ali-Abadi M, Shakeri M, Kimiagar M, Salek R, et al. Association between Malnutrition and Depression in Elderly People in Razavi Khorasan: A Population Based-Study in Iran. Iran J Public Health. 2011;40(2):67–74. PMID23113074
  20. Vafaei Z, Mokhtari H, Sadooghi Z, Meamar R, Chitsaz A, Moeini M. Malnutrition is associated with depression in rural elderly population. J Res Med Sci. 2013 Mar;18(Suppl 1):S15-9. PMID23961277
  21. Vidyalakshmi M, Kirubhakaran B. Assessment of Nutritional Status and Its Associated Factors in Elderly in Rural Area of Tamil Nadu, India. Galore International Journal of Health Sciences and Research. 2021;6(1):38–43.DOI 10.52403/GIJHSR.20210107
  22. Nho JH, Kim SR, Kwon YS. Depression and appetite: predictors of malnutrition in gynecologic cancer. Support Care Cancer. 2014 Nov;22(11):3081–8.DOI 10.1007/s00520-014-2340-yPMID24986204
  23. Belujon P, Grace AA. Dopamine system dysregulation in major depressive disorders. International Journal of Neuropsychopharmacology. 2017 Dec 1;20(12):1036–46. DOI 10.1093/ijnp/pyx056
  24. Hildebrand P, Königschulte W, Gaber TJ, Bubenzer-Busch S, Helmbold K, Biskup CS, et al. Effects of dietary tryptophan and phenylalanine–tyrosine depletion on phasic alertness in healthy adults–A pilot study. Food Nutr Res. 2015;59(1):26407. DOI https://doi.org/10.3402%2Ffnr.v59.26407
  25. Li X, Liu H, Li D, Lei H, Wei X, Schlenk D, et al. Dietary seleno-methionine causes alterations in neurotransmitters, ultrastructure of the brain, and behaviors in zebrafish. Environ Sci Technol [Internet]. 2021 Sep 7;55(17):11894–905. DOI 10.1021/acs.est.1c03457
  26. Kalkman HO, Hersberger M, Walitza S, Berger GE. Disentangling the molecular Mechanisms of the antidepressant activity of omega-3 polyunsaturated fatty acid: a comprehensive review of the literature. Int J Mol Sci [Internet]. 2021 Apr 22;22(9):4393. DOI 10.3390/ijms22094393
  27. Trautmann C, Bock A, Urbach A, Hübner CA, Engmann O. Acute vitamin B12 supplementation evokes antidepressant response and alters Ntrk-2. Neuropharmacology. 2020 Jul;171:108112. DOI 10.1016/j.neuropharm.2020.108112
  28. Qiao M, Jiang QS, Liu YJ, Hu XY, Wang LJ, Zhou QX, et al. Antidepressant mechanisms of venlafaxine involving increasing histone acetylation and modulating tyrosine hydroxylase and tryptophan hydroxylase expression in hippocampus of depressive rats. Neuroreport. 2019 Mar 6;30(4):255–61. DOI 10.1097/WNR.0000000000001191
  29. Kong L, Shen Y, Hu S, Lai J. The impact of quetiapine monotherapy or in combination with lithium on the thyroid function in patients with bipolar depression: A retrospective study. CNS Neurosci Ther. 2023; DOI https://doi.org/10.1111/cns.14342
  30. Rémond D, Shahar DR, Gille D, Pinto P, Kachal J, Peyron MA, et al. Understanding the gastrointestinal tract of the elderly to develop dietary solutions that prevent malnutrition. Oncotarget [Internet]. 2015 Jun 10;6(16):13858–98. DOI 10.18632/oncotarget.4030
  31. Keck MM, Vivier H, Cassisi JE, Dvorak RD, Dunn ME, Neer SM, et al. Examining the role of anxiety and depression in dietary choices among college students. Nutrients. 2020;12(7):2061
  32. Mokhber N, Majdi M, Ali-Abadi M, Shakeri M, Kimiagar M, Salek R, et al. Association between Malnutrition and Depression in Elderly People in Razavi Khorasan: A Population Based-Study in Iran. Iran J Public Health. 2011;40(2):67–74. PMID23113074

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