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HUBUNGAN RASIO LP/TB (LINGKAR PINGGANG TERHADAP TINGGI BADAN) DENGAN RASIO KADAR TG/HDL PADA REMAJA OBES SENTRAL

1Departemen Ilmu Gizi, Fakultas Kedokteran, Universitas Diponegoro, Indonesia

2Program Studi Gizi, Fakultas Ilmu Keperawatan dan Kesehatan, Universitas Muhammadiyah Semarang, Indonesia

3Bagian Biokimia, Fakultas Kedokteran, Universitas Diponegoro, Indonesia

Received: 8 May 2020; Published: 4 Jun 2020.

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Abstract

Latar belakang: Penanda aterogenik dan resistensi insulin pada subjek obesitas sentral yang akurat dan aplikatif dapat menggunakan rasio TG/HDL. Penelitian sebelumnya telah banyak diteliti tentang pemeriksaan HOMA-IR pada subjek dengan resistensi insulin. Rasio LP/TB diketahui lebih unggul dalam memprediksi risiko penyakit jantung koroner dibandingkan LP saja karena rasio ini merupakan indeks yang stabil pada ras, umur, dan jenis kelamin berbeda. Saat ini penelitian tentang hubungan rasio LP/TB dengan rasio TG/HDL pada subjek remaja obes masih terbatas.

Tujuan: Penelitian ini bertujuan mengetahui hubungan rasio LP/TB dengan rasio TG/HDL pada remajadengan obesitas sentral.

Metode: Penelitian ini merupakan penelitian observasional dengan desain cross sectional. Penelitian dilakukan di Universitas Diponegoro, Semarang. Kriteria inklusi meliputi, remaja perempuan atau laki-laki, berusia 19-20 tahun,memiliki IMT > 25kg/m2 dan lingkar pingang >80cm untuk perempuan dan >90 cm untuk laki-laki. Berat badan menggunakan alat bio impedance analyzer. LP diukur menggunakan pita metlin statis. Pengambilan sampel darah untuk TG dan HDL melalui vena, setelah puasa semalam (10 jam) kemudian diuji menggunakan autoanalyzer. Data dianalisis menggunakan uji Pearson dan Spearman rank test.

Hasil: Kami menganalisis pada 56 remaja dengan obesitas sentral. Rerata LP (88,9 ± 8,67cm), kadar TG (105 ± 56,62mg/dL), HDL-c (45,3 ± 12,61mg/dL), rasio LP/TB (0,55 ± 0,04), rasio TG/HDL 2,3 ± 1,42). Ada hubungan signifikan antara rasio LP/TB dengan TG/HGL (r=0,386; p=0,003)

Simpulan: Rasio LP/TB tinggi berkorelasi dengan peningkatan rasio TG/HDL-C pada remaja dengan obesitas sentral dan dapat digunakan sebagai penanda awal resiko metabolik

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Keywords: rasio LP/TB; rasio TG/HDL; remaja; obes sentral

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