DOI: https://doi.org/10.14710/jnc.v9i2.27487

HUBUNGAN RASIO LP/TB (LINGKAR PINGGANG TERHADAP TINGGI BADAN) DENGAN RASIO KADAR TG/HDL PADA REMAJA OBES SENTRAL

1Departemen Ilmu Gizi, Fakultas Kedokteran, Universitas Diponegoro, Indonesia

2Program Studi Gizi, Fakultas Ilmu Keperawatan dan Kesehatan, Universitas Muhammadiyah Semarang, Indonesia

3Bagian Biokimia, Fakultas Kedokteran, Universitas Diponegoro, Indonesia

Received: 8 May 2020; Published: 4 Jun 2020.

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Abstract

Latar belakang: Penanda aterogenik dan resistensi insulin pada subjek obesitas sentral yang akurat dan aplikatif dapat menggunakan rasio TG/HDL. Penelitian sebelumnya telah banyak diteliti tentang pemeriksaan HOMA-IR pada subjek dengan resistensi insulin. Rasio LP/TB diketahui lebih unggul dalam memprediksi risiko penyakit jantung koroner dibandingkan LP saja karena rasio ini merupakan indeks yang stabil pada ras, umur, dan jenis kelamin berbeda. Saat ini penelitian tentang hubungan rasio LP/TB dengan rasio TG/HDL pada subjek remaja obes masih terbatas.

Tujuan: Penelitian ini bertujuan mengetahui hubungan rasio LP/TB dengan rasio TG/HDL pada remajadengan obesitas sentral.

Metode: Penelitian ini merupakan penelitian observasional dengan desain cross sectional. Penelitian dilakukan di Universitas Diponegoro, Semarang. Kriteria inklusi meliputi, remaja perempuan atau laki-laki, berusia 19-20 tahun,memiliki IMT > 25kg/m2 dan lingkar pingang >80cm untuk perempuan dan >90 cm untuk laki-laki. Berat badan menggunakan alat bio impedance analyzer. LP diukur menggunakan pita metlin statis. Pengambilan sampel darah untuk TG dan HDL melalui vena, setelah puasa semalam (10 jam) kemudian diuji menggunakan autoanalyzer. Data dianalisis menggunakan uji Pearson dan Spearman rank test.

Hasil: Kami menganalisis pada 56 remaja dengan obesitas sentral. Rerata LP (88,9 ± 8,67cm), kadar TG (105 ± 56,62mg/dL), HDL-c (45,3 ± 12,61mg/dL), rasio LP/TB (0,55 ± 0,04), rasio TG/HDL 2,3 ± 1,42). Ada hubungan signifikan antara rasio LP/TB dengan TG/HGL (r=0,386; p=0,003)

Simpulan: Rasio LP/TB tinggi berkorelasi dengan peningkatan rasio TG/HDL-C pada remaja dengan obesitas sentral dan dapat digunakan sebagai penanda awal resiko metabolik

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Keywords: rasio LP/TB; rasio TG/HDL; remaja; obes sentral

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  11. Widyastuti N, Dieny FF, Fitranti DY. Asupan lemak jenuh dan serat pada remaja obesitas kaitannya dengan sindrom metabolik. Jurnal Gizi Klinik Indonesia. 2016;12(4):131–7
  12. Mexitalia M. The risk factor of obesity on adolescence (the role of energy expenditure and polymorphism of uncoupling protein 2 and 3 genes). Dissertation: Post Graduated Diponegoro University; 2010
  13. Grundy SM, Becker D, Clark LT, Cooper RS, Denke MA, James Howard W, et al. Third Report of the National Cholesterol Education Program (NCEP). 2002
  14. Silvana C, Miralles W, Wollinger LM, Marin D, Genro JP, Contini V, et al. Waist-to-Height Ratio (WHtR) and Triglyceride to HDL-c ratio (TG/HDL-c) as predictors of cardiometabolic risk. Nutr Hosp. 2015;31(5):2115–21
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  16. Shen S, Lu Y, Qi H, Li F, Shen Z, Wu L, et al. Waist-to-height ratio is an effective indicator for comprehensive cardiovascular health. Nature. 2017;1–7
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  22. Björnson E, Adiels M, Taskinen MR, Borén J. Kinetics of plasma triglycerides in abdominal obesity. Curr Opin Lipidol. 2017;28(1):11–8
  23. Yoo E. Waist-to-Height Ratio as A Screening Tool for Obesity and Cardiometabolic Risk. Korean J Pediatr. 2016;59(11):425–31
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  25. Ashwell M, Gibson S. Waist-to-height Ratio as An Indicator of Early Health Risk : Simpler and More Predictive Than Using A Matrix Based on BMI and Waist Circumference. Br Med J. 2016;6:1–7
  26. Matarese LE, Pories WJ. Adult Weight Loss Diets: Metabolic Effects and Outcomes. Nutr Clin Pract. 2014;XX:1–9

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