DOI: https://doi.org/10.14710/dmj.v15i4.53896

ASSOCIATION BETWEEN ADMISSION D-DIMER LEVELS AND MORTALITY IN COVID-19

*Amanatus Solikhhah orcid scopus publons  -  Department of Clinical Pathology, Faculty of Medicine, Ahmad Dahlan University, Indonesia
Rizka Ariani  -  Department of Microbiology, Faculty of Medicine, Ahmad Dahlan University, Indonesia, Indonesia
Mulat Muliasih  -  Department of Clinical Pathology, Faculty of Medicine, Malahayati University, Indonesia, Indonesia
Open Access Copyright 2026 Amanatus - Solikhhah
Creative Commons License This work is licensed under a Creative Commons Attribution-NonCommercial-ShareAlike 4.0 International License.

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Abstract

Background: It is possible that specific laboratory test results could indicate the likelihood of death from COVID-19. Objective: The main goal of this research was to figure out if measuring D-dimer levels could help forecast the likelihood of death for individuals suffering from COVID-19. Methods: A backward-looking study of a group of people based on observations, encompassing 317 individuals, was conducted utilizing existing data extracted from the health documents of COVID-19 inpatients. The concentration of D-dimer was acquired via patient's blood test results upon initial admittance to the medical facility. Following this, patients were divided into two categories: those who lived (comprising 252 individuals) and those who did not (consisting of 66 individuals), according to the end result. Proportions and central values were assessed employing Kolmogorov-Smirnov. Logistic regression was applied to ascertain if there exists a noteworthy disparity in D-dimer concentrations among different mortality statuses. Results: The cohort that did not survive showed a notably elevated presence of D-dimer (Odds Ratio 6.480 ;p<0.001). Conclusion: The starting assessment of D-dimer levels might be useful in spotting individuals who face increased vulnerability and help guide choices concerning critical care management.

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Keywords: COVID-19;D-dimer;mortality
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