FACTORS INFLUENCING TREATMENT OUTCOMES OF DRUG-SENSITIVE TUBERCULOSIS PATIENTS: STUDY IN R.A. KARTINI HOSPITAL, JEPARA, INDONESIA

Bambang Hariyana; Soeharyo Hadisaputro; Amin Husni; Winarto Winarto; Endang Mahati; Ari Budi Himawan

doi:10.14710/dmj.v14i5.51448

DOI: https://doi.org/10.14710/dmj.v14i5.51448

FACTORS INFLUENCING TREATMENT OUTCOMES OF DRUG-SENSITIVE TUBERCULOSIS PATIENTS: STUDY IN R.A. KARTINI HOSPITAL, JEPARA, INDONESIA

*Bambang Hariyana

- 1. Doctoral student in Medical and Health Sciences, Faculty of Medicine, Diponegoro University, Indonesia

Soeharyo Hadisaputro - Department of Public Health Science - Preventive Medicine, Faculty of Medicine, Universitas Diponegoro, Semarang, Indonesia, Indonesia

Amin Husni - Department of Neurology, Faculty of Medicine, Universitas Diponegoro, Semarang, Indonesia, Indonesia

Winarto Winarto - Department of Microbiology, Faculty of Medicine, Universitas Diponegoro, Semarang, Indonesia, Indonesia

Endang Mahati - Department of Pharmacology, Faculty of Medicine, Universitas Diponegoro, Semarang, Indonesia, Indonesia

Ari Budi Himawan - Department of Public Health Science—Preventive Medicine, Faculty of Medicine, Universitas Diponegoro, Semarang, Indonesia

This work is licensed under a Creative Commons Attribution-NonCommercial-ShareAlike 4.0 International License.

BibTex Citation Data :

@article{dmj51448,
    author = {Bambang Hariyana and Soeharyo Hadisaputro and Amin Husni and Winarto Winarto and Endang Mahati and Ari Budi Himawan},
    title = {FACTORS INFLUENCING TREATMENT OUTCOMES OF DRUG-SENSITIVE TUBERCULOSIS PATIENTS: STUDY IN R.A. KARTINI HOSPITAL, JEPARA, INDONESIA},
    journal = {Jurnal Kedokteran Diponegoro (Diponegoro Medical Journal)},
  volume = {14},
    number = {5},
    year = {2025},
    keywords = {TB treatment outcomes, age, employment, TB-HIV},
    abstract = {   Introduction:  Tuberculosis (TB) is an infectious and chronic disease with the highest mortality rate after ischemic heart disease and cerebrovascular disease. Indonesia has become the second-ranked worldwide for the highest estimated new TB cases. The TB treatment success rate (Treatment Success Rate/TSR) in Central Java Province stands at 87%, which is below the target of 90%. This study aims to provide an overview of the characteristics of TB patients at R.A. Kartini Hospital and the factors that influence the results of pulmonary TB therapy.   Methods : This study is descriptive-analytical with a cross-sectional approach, using secondary data from the Tuberculosis Information System of R.A. Kartini Hospital from January 2023 to December 2023. Data were processed and analyzed using SPSS.   Results:  The average age of subjects was 39.26 ± 19.36, of which the majority were male (58.5%). Data showed that 58.1% of subjects had jobs, and the majority of subjects had no history of diabetes mellitus (DM) or human immunodeficiency virus (HIV) (86.6% and 96.7%, respectively). All subjects received tuberculosis (TB) treatment; most recovered (76.4%). Based on body mass index (BMI), 50.8% had a normal nutritional status. Chi-square test analysis showed a significant relationship between age and employment status with the success rate of TB treatment. However, the bivariate logistic regression analysis demonstrated that age was significantly related to TB treatment outcomes with an odds ratio (OR) of 1.033 ( p  = 0.000). Employment status revealed significant results; working subjects were 2.261 times more likely to experience suboptimal treatment outcomes ( p  = 0.013). Moreover, HIV history showed a significant relationship with TB treatment outcomes after adjusting for age with multivariate logistic regression analysis.   Conclusion:  Several factors were significantly related to TB treatment outcomes, such as age, employment status, and TB-HIV co-infection.  },
   issn = {2540-8844},   pages = {254--261}  doi = {10.14710/dmj.v14i5.51448},
    url = {https://ejournal3.undip.ac.id/index.php/medico/article/view/51448}
}

Citation Format:

Abstract

Introduction: Tuberculosis (TB) is an infectious and chronic disease with the highest mortality rate after ischemic heart disease and cerebrovascular disease. Indonesia has become the second-ranked worldwide for the highest estimated new TB cases. The TB treatment success rate (Treatment Success Rate/TSR) in Central Java Province stands at 87%, which is below the target of 90%. This study aims to provide an overview of the characteristics of TB patients at R.A. Kartini Hospital and the factors that influence the results of pulmonary TB therapy.

Methods: This study is descriptive-analytical with a cross-sectional approach, using secondary data from the Tuberculosis Information System of R.A. Kartini Hospital from January 2023 to December 2023. Data were processed and analyzed using SPSS.

Results: The average age of subjects was 39.26 ± 19.36, of which the majority were male (58.5%). Data showed that 58.1% of subjects had jobs, and the majority of subjects had no history of diabetes mellitus (DM) or human immunodeficiency virus (HIV) (86.6% and 96.7%, respectively). All subjects received tuberculosis (TB) treatment; most recovered (76.4%). Based on body mass index (BMI), 50.8% had a normal nutritional status. Chi-square test analysis showed a significant relationship between age and employment status with the success rate of TB treatment. However, the bivariate logistic regression analysis demonstrated that age was significantly related to TB treatment outcomes with an odds ratio (OR) of 1.033 (p = 0.000). Employment status revealed significant results; working subjects were 2.261 times more likely to experience suboptimal treatment outcomes (p = 0.013). Moreover, HIV history showed a significant relationship with TB treatment outcomes after adjusting for age with multivariate logistic regression analysis.

Conclusion: Several factors were significantly related to TB treatment outcomes, such as age, employment status, and TB-HIV co-infection.

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FACTORS INFLUENCING TREATMENT OUTCOMES OF DRUG-SENSITIVE TUBERCULOSIS PATIENTS: STUDY IN R.A. KARTINI HOSPITAL, JEPARA, INDONESIA

Subject	TB treatment outcomes, age, employment, TB-HIV
Type	Research Results
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Keywords: TB treatment outcomes, age, employment, TB-HIV

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Section: Original Articles

Language : EN

In Vol 14, No 5 (2025): JURNAL KEDOKTERAN DIPONEGORO (DIPONEGORO MEDICAL JOURNAL)

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