DOI: https://doi.org/10.14710/dmj.v12i6.40711

Literature Review: The Role of Saffron (Crocus sativus L) in Cosmetic Dermatology

*Galih Sari Damayanti  -  "Department of Dermatology Venereology and Aesthetic, Universitas Diponegoro, Jl. Prof. Sudarto, SH, Tembalang, Semarang, Indonesia 50275", Indonesia
Puguh Riyanto scopus  -  "Department of Dermatology Venereology and Aesthetic, Universitas Diponegoro, Jl. Prof. Sudarto, SH, Tembalang, Semarang, Indonesia 50275", Indonesia

Citation Format:
Abstract

Background : Crocus sativus L known as saffron is widely discussed in Indonesia. Although saffron has been used since ancient times for medicinal and cosmetic purposes, scientific research on the mechanism of saffron in its role in promoting skin health is lacking. Objectives : This literature review is to determine the role of saffron in cosmetic dermatology. Methods : This article is a narrative research. The library sources that used was carried out through the database Google Scholar, PubMed, and Cochrane. The article search does not limit study design or study level. All articles were searched from 2012 to June 2023. The study inclusion criteria included: data available in English and Indonesian. Exclusion criteria were articles on the benefits of using saffron in the other field of dermatology and the use of saffron in combination with other topical active ingredients. Results : There were 16 articles which meet the criterias. It was found that saffron play role in the cosmetic dermatology such as in skin aging, melasma, as a photoprotection agents, skin moisturizer, prevention and treatment of skin cancer, as well as preparation of cosmetic products. Saffron has antioxidant, antiinflammatory, antipigmentation, antiwrinkle, anticarcinogenic and photoprotective activities. Conclusion : Crocus sativus L is a natural ingredient that has the potential to be further developed into medicinal forms, both oral and topical preparations because it is proven to have various pharmacological effects that play role in the cosmetic dermatology.

Fulltext View|Download
Keywords: Active Ingredients; Cosmetics; Cosmetic Dermatology; Role; Saffron
Funding: Universitas Diponegoro

Article Metrics:

Article Info
Section: Original Articles
Language : EN
Recent articles
Literature Review: The Role of Saffron (Crocus sativus L) in Cosmetic Dermatology The Effect of Moringa oleifera Extract on Histopathological of Mice Testes Exposed by Monosodium Glutamate The Difference of Risk Factors Between Mild and Moderate-Severe Refractive Errors in Pediatric Patients at the Diponegoro National Hospital Case Report : Chromoblastomycosis More recent articles
  1. Lestari F. :: repository.unisba.ac.id :: Bunga Rampai Chapter Progr Stud Farm Menggali Kandidat Bahan Alam Sebagai Obat Mod Asli Indones dan Metod Potensial dalam Pengemb Sediaan Farm Repos UNISBA.ac.id. 2022;2(2):7-11
  2. Nanda S, Madan K. The role of Safranal and saffron stigma extracts in oxidative stress, diseases and photoaging: A systematic review. Heliyon. 2021;7(2):e06117. doi: 10.1016/j.heliyon.2021.e06117
  3. Mzabri I, Addi M. cosmetics Traditional and Modern Uses of Saffron ( Crocus. Cosmetics. 2019;6(63):1-11
  4. Salvi A, Minerva P. Kelayakan Sediaan Penyegar (Face Toner) Putik Bunga Saffron (Crocus Sativus) Sebagai Kosmetik Tradisional Perawatan Kulit Wajah. J Tata Rias dan Kecantikan. 2022;3(1):1. doi: 10.24036/.v3i1.54
  5. Xiong J, Grace MH, Kobayashi H, Lila MA. Evaluation of saffron extract bioactivities relevant to skin resilience. J Herb Med. 2023;37(October 2022):100629. doi: 10.1016/j.hermed.2023.100629
  6. Roniawati, I, Putriana NA, Putri AN NY. Review : Bioactivities of Saffron as an Active Ingredient in Cosmetics. Indones J Pharm. 2021;3(2):74-81
  7. Peraturan BPOM No 32 Tahun 2019 Tentang Persyaratan Keamanan Dan Mutu Obat Tradisional. Badan pengawas obat dan makanan republik indonesia. Bpom Ri. 2021;11:1-16
  8. Campa M, Baron E. Anti-aging effects of select botanicals: Scientific evidence and current trends. Cosmetics. 2018;5(3):1-15. doi: 10.3390/COSMETICS5030054
  9. Afifah MN, Hasanah AN. Saffron (Crocus sativus L): Kandungan dan Aktivitas Farmakologinya. Maj Farmasetika. 2020;5(3):116-123. doi: 10.24198/mfarmasetika.v5i3.26291
  10. Zarkogianni M, Nikolaidis N. Determination of Sun Protection Factor (SPF) and Stability of Oil-in-Water Emulsions Containing Greek Red Saffron (Crocus Sativus L.) as a Main Antisolar Agent. Int J Adv Res Chem Sci. 2016;3(7):1-7. doi: 10.20431/2349-0403.0307001
  11. Runger T. Ultraviolet Radiation. 4th ed. (Bolognia J, Schaffer J CL, ed.). Elsevier Ltd; 2018
  12. T R. Cutaneous Photobiology. Fitzpatrick. (Kang S, Amagai M, Bruckner A, Enk A, Margolis D, McMichael A, et al., ed.). McGraw-Hill; 2019
  13. Kulka M. Mechanisms and Treatment of Photoaging and Photodamage. Using Old Solutions to New Problems - Natural Drug Discovery in the 21st Century. InTech; 2013
  14. Rigi H, Mohtashami L, Asnaashari M, Emami SA, Tayarani-Najaran Z. Dermoprotective Effects of Saffron: A Mini Review. Curr Pharm Des. 2021;27(46):4693-4698. doi: 10.2174/1381612827666210920150855
  15. Rathee P, Kumar S, Kumar D, Kumari B, Yadav SS. Skin hyperpigmentation and its treatment with herbs: an alternative method. Futur J Pharm Sci. 2021;7(1). doi: 10.1186/s43094-021-00284-6
  16. Kaur A, Singh TG, Dhiman S, Arora S, Babbar R. Novel herbs used in cosmetics for skin and hair care : A review. Plant Arch. 2020;20:3784-3793
  17. Akhtar N, Khan HMS, Ashraf S, Mohammad IS, Ali A. Skin depigmentation activity of crocus sativus extract cream. Trop J Pharm Res. 2014;13(11):1803-1808. doi: 10.4314/tjpr.v13i11.5
  18. Fagot D, Pham DM, Laboureau J, et al. Crocin, a natural molecule with potentially beneficial effects against skin ageing. Int J Cosmet Sci. 2018;40(4):388-400. doi: 10.1111/ics.12472
  19. Deng M, Li D, Zhang Y, et al. Protective effect of crocin on ultraviolet B-induced dermal fibroblast photoaging. Mol Med Rep. 2018;18(2):1439-1446. doi: 10.3892/mmr.2018.9150
  20. Golmohammadzadeh S, Hosseinzadeh H. ive. 2010;(April)
  21. Abdalla MA. Melasma Clinical Features, Diagnosis, Epidemiology and Etiology: An Update Review. Siriraj Med J. 2021;73(12):841-850. doi: 10.33192/SMJ.2021.109
  22. Michelle Rodrigues GPA. Melasma. 9th Fitzpa. (Sewon Kang, Masayuki Amagai et al, ed.). New York: Elsevier; 2019
  23. Yin W, Zhao F, He Y, Lai H, Sun M. The mechanism of Croci stigma in the treatment of melasma based on network pharmacology and molecular docking. J Cosmet Dermatol. 2023;22(7):2105-2114. doi: 10.1111/jocd.15682
  24. Akhtar N, Khan HMS, Ashraf S, Mohammad IS, Saqib NU, Bashir K. Moisturizing effect of stable cream containing Crocus sativus extracts. Pak J Pharm Sci. 2014;27(6):1881-1884
  25. Rahmani AH, Khan AA, Aldebasi YH. Saffron (Crocus sativus) and its active ingredients: Role in the prevention and treatment of disease. Pharmacogn J. 2014;9(6):873-879. doi: 10.5530/pj.2017.6.137
  26. Wagh JG, Veerkar P V, Mittal A, Kumari R, Sharma S, Sharma S. Preparation and evaluation of modified herbal “Kumkum Powder” to reduce allergic reactions. Int J Health Sci (Qassim). 2022;6(July):11274-11283. doi: 10.53730/ijhs.v6ns5.11267
  27. Mahanthesh MC. MAS ;Shinde. MV. SAS. DJI. NBU. AWC. Design, Development and Assessment of Herbal Lipstick from Natural Pigment. Int J Pharm Sci Rev Res. 2020;61(1):59-64
  28. K VL, K TK, K NR. Study of Crocus sativus as Complexion Promoter in Skin Care. Int J Pharm Clin Res. 2010;2(2):76-79. www.ijpcr.com

Last update:

No citation recorded.

Last update:

No citation recorded.