BibTex Citation Data :
@article{dmj29346, author = {Tiffani Wignjosoesastro and Widyawati Widyawati and Rahmat Sugianto}, title = {THE EFFECT OF GLYCOLIC ACID AND VITAMIN C TOPICAL IN FRECKLES EFFICACY}, journal = {Jurnal Kedokteran Diponegoro (Diponegoro Medical Journal)}, volume = {10}, number = {1}, year = {2021}, keywords = {Freckles, Ephelides, Glycolic Acid, Vitamin C}, abstract = { Abstract Background: Freckles are small dark-spot hyperpigmentation on the face, upper body, and back of the hands. This hyperpigmentation develops as a result of melanocyte activity by the combination of genetic predisposition located on the basal layer and sun exposure. Glycolic acid and vitamin C are widely used as a depigmentation agent. The component of vitamin C is unstable, hence, it is often used more effective when it binds to other depigmentation agents, such as glycolic acid to develop better depigmentation Objective: The aim of this study was to prove the efficacy of combination of glycolic acid and vitamin C in freckles. Methods: True experimental study with one group pre and post-test group design. Fifteen freckles patients with inclusion and exclusion criteria received combination therapy of glycolic acid and vitamin C topical for 30 days. Clinical evaluation using Freckles Refinement Score and photography was recorded before and after therapy. The statistical analyses used was Wilcoxon test. Results: There was a significant value ( p = 0.000) for improvement of the Freckles Refinement Score after received the combination of glycolic acid and vitamin C topical. Conclusion: The combination of glycolic acid and vitamin C was effective for Freckles. }, issn = {2540-8844}, pages = {51--54} doi = {10.14710/dmj.v10i1.29346}, url = {https://ejournal3.undip.ac.id/index.php/medico/article/view/29346} }
Refworks Citation Data :
Abstract
Background: Freckles are small dark-spot hyperpigmentation on the face, upper body, and back of the hands. This hyperpigmentation develops as a result of melanocyte activity by the combination of genetic predisposition located on the basal layer and sun exposure. Glycolic acid and vitamin C are widely used as a depigmentation agent. The component of vitamin C is unstable, hence, it is often used more effective when it binds to other depigmentation agents, such as glycolic acid to develop better depigmentation
Objective: The aim of this study was to prove the efficacy of combination of glycolic acid and vitamin C in freckles.
Methods: True experimental study with one group pre and post-test group design. Fifteen freckles patients with inclusion and exclusion criteria received combination therapy of glycolic acid and vitamin C topical for 30 days. Clinical evaluation using Freckles Refinement Score and photography was recorded before and after therapy. The statistical analyses used was Wilcoxon test.
Results: There was a significant value (p = 0.000) for improvement of the Freckles Refinement Score after received the combination of glycolic acid and vitamin C topical.
Conclusion: The combination of glycolic acid and vitamin C was effective for Freckles.
Article Metrics:
Last update:
JURNAL KEDOKTERAN DIPONEGORO (DIPONEGORO MEDICAL JOURNAL) by http://ejournal3.undip.ac.id/index.php/medico/ is licensed under a Creative Commons Attribution-NonCommercial-ShareAlike 4.0 International License.
