DOI: https://doi.org/10.14710/jnc.v15i2.53185

HUBUNGAN ANTARA STATUS GIZI DENGAN KUALITAS HIDUP PASIEN GAGAL GINJAL KRONIS DENGAN HEMODIALISA DI RSUP DR. MOHAMMAD HOESIN

Prodi Gizi, Fakultas Kesehatan Masyarakat, Universitas Sriwijaya, Ogan Ilir, Sumatera Selatan, Indonesia

Received: 24 Sep 2025; Revised: 26 Feb 2026; Accepted: 27 Feb 2026; Available online: 30 Apr 2026; Published: 12 May 2026.

Citation Format:
Abstract

ABSTRACT

Background: Chronic Kidney Disease (CKD) is a non-communicable disease with increasing prevalence in Indonesia and globally. Hemodialysis therapy for end-stage CKD can prolong life expectancy, but it impacts patients' quality of life. Nutritional status is known to influence the quality of life of hemodialysis patients, but previous research has shown discrepancies.

Objectives: This study aims to analyze the relationship between nutritional status and quality of life of CKD patients undergoing hemodialysis at Mohammad Hoesin Central General Hospital.

Methods: This study used a cross-sectional design with 49 respondents selected through purposive sampling. Data were collected through body mass index (BMI) measurements and the KDQOL-SF 1.3 questionnaire. Nutritional status was categorized as good and malnourished, while quality of life was classified as good and poor. Bivariate analysis used Chi-Square test.

Results: The majority of respondents were female, unemployed, had undergone hemodialysis for >1 year, were on hemodialysis twice a week for more than >4 hours, had a good nutritional status (71,4%), and a good quality of life (73,5%). There was a significant relationship between nutritional status and quality of life (p = 0,004), with a PR value of 2,000 (95% CI: 1,076–3,717), indicating that patients with good nutritional status were twice as likely to have a good quality of life compared to malnourished patients.

Conclusion: Nutritional status is significantly associated with the quality of life of patients with Chronic Kidney Disease (CKD) on hemodialysis. Optimal nutritional management is a crucial aspect in improving the quality of life of hemodialysis patients.

Keywords: Chronic kidney disease; hemodialysis; quality of life; nutritional status

 

ABSTRAK

Latar belakang: Gagal Ginjal Kronis (GGK) merupakan salah satu penyakit tidak menular yang prevalensinya meningkat di Indonesia dan dunia. Terapi hemodialisa sebagai penanganan GGK stadium akhir dapat memperpanjang harapan hidup, namun berdampak pada kualitas hidup pasien. Status gizi diketahui berpengaruh terhadap kualitas hidup pasien hemodialisa, tetapi hasil penelitian sebelumnya masih menunjukkan kesenjangan.

Tujuan: Penelitian ini bertujuan untuk menganalisis hubungan antara status gizi dengan kualitas hidup pasien GGK dengan hemodialisa di RSUP Dr. Mohammad Hoesin.

Metode: Penelitian ini menggunakan desain cross-sectional dengan jumlah responden sebanyak 49 orang yang dipilih melalui teknik purposive sampling. Data dikumpulkan melalui pengukuran indeks massa tubuh (IMT) dan kuesioner KDQOL-SF 1.3. Status gizi dikategorikan menjadi normal dan malnutrisi, sedangkan kualitas hidup dikategorikan menjadi baik dan buruk. Analisis bivariat menggunakan uji Chi-Square.

Hasil: Mayoritas responden berjenis kelamin perempuan, tidak bekerja, sudah melakukan hemodialisa >1 tahun, melakukan hemodialisa 2 kali seminggu dengan durasi >4 jam, memiliki status gizi normal (71,4%) dan kualitas hidup baik (73,5%). Terdapat hubungan yang signifikan antara status gizi dengan kualitas hidup (p = 0,004), dengan nilai PR = 2,000 (CI 95%: 1,076–3,717), menunjukkan bahwa pasien dengan status gizi normal berpeluang dua kali lebih besar untuk memiliki kualitas hidup yang baik dibandingkan pasien malnutrisi.

Simpulan: Status gizi berhubungan signifikan dengan kualitas hidup pasien GGK yang menjalani hemodialisa. Manajemen gizi yang optimal menjadi aspek penting dalam meningkatkan kualitas hidup pasien hemodialisa.

Kata Kunci : Gagal ginjal kronis; hemodialisa; kualitas hidup; status gizi

Note: This article has supplementary file(s).

Fulltext View|Download |  common.other
Surat Pernyataan Keaslian
Subject
Type Other
  Download (74KB)    Indexing metadata
 common.other
Turnitin
Subject
Type Other
  Download (1MB)    Indexing metadata
 common.other
Surat Kaji Etik FKM
Subject
Type Other
  Download (570KB)    Indexing metadata
 common.other
Surat Kaji Etik RSMH
Subject
Type Other
  Download (49KB)    Indexing metadata
 Data Set
Data penelitian
Subject
Type Data Set
  Download (60KB)    Indexing metadata
Email colleagues
Keywords: Gagal ginjal kronis; hemodialisa; kualitas hidup; status gizi

Article Metrics:

Article Info
Section: Articles
Language : ID
  1. Utama F, Rahmiwati A, Alamsari H, Lihwana MA. Gambaran Penyakit Tidak Menular di Universitas Sriwijaya. Jurnal Kesehatan. 2018;11(2):52–64. https://doi.org/10.23917/jk.v11i2.7593
  2. Sudayasa IP, Rahman MF, Eso A, Jamaluddin, Parawansah, Alifariki LO, et al. Deteksi Dini Faktor Risiko Penyakit Tidak Menular pada Masyarakat Desa Andepali Kecamatan Sampara Kabupaten Konawe. Journal of Community Engagement in Health. 2020;3(1):60–6. https://doi.org/10.30994/jceh.v3i1.37
  3. WHO. World Health Organization. 2023 [cited 2024 Mar 3]. Noncommunicable diseases. Available from: https://www.who.int/news-room/fact-sheets/detail/noncommunicable-diseases
  4. International Society Nephrology. Global Kidney Health Atlas 2023. Belgia: International Society of Nephrology; 2023
  5. Tim Riskesdas 2018. Laporan Nasional Riskesdas 2018. Jakarta: Lembaga Penerbit Badan Penelitian dan Pengembangan Kesehatan; 2019
  6. Pernefri. 11th Report of Indonesian Renal Registry. Jakarta: Perhimpunan Nefrologi Indonesia; 2018
  7. Rosini DD, Aini, Ramadanti E. Efektivitas Hemodialisa Berdasarkan Parameter Hemoglobin, Eritrosit, dan Hematokrit Pada Penderita Gagal Ginjal Kronik. Jurnal Analis Medika Biosains (JAMBS). 2020;7(2):146–52. https://doi.org/10.32807/jambs.v7i2.198
  8. Tambunan EH, Siagian E. Depresi, Kecemasan, Stres dan Kualitas Hidup Pasien Gagal Ginjal Kronik yang Menjalani Hemodialisa. MAHESA. 2023;3(2):563–71. https://doi.org/10.33024/mahesa.v3i2.9709
  9. Juwita L, Kartika IR. Pengalaman Menjalani Hemodialisa Pada Pasien Chronic Kidney Disease. Jurnal Endurance : Kajian Ilmiah Problema Kesehatan. 2019;4(1):97–106. https://doi.org/10.22216/jen.v4i1.1298
  10. WHO. World Health Organization. 2024 [cited 2026 Feb 18]. Malnutririon. Available from: https://www.who.int/news-room/fact-sheets/detail/malnutrition
  11. Utami AS, Asmara IGY, Irawati D. Hubungan Adekuasi Hemodialisis dengan Status Gizi Pasien Penyakit Ginjal Kronis yang Menjalani Hemodialisis Reguler di RSUD Kota Mataram. Jurnal Kedokteran Unram. 2021;10(3):502–8. https://doi.org/10.29303/jku.v10i3
  12. Sembiring LP, Hanifah ZN. Hubungan Status Gizi terhadap Kualitas Hidup pada Pasien Penyakit Ginjal Kronik yang Menjalani Hemodialisis di RSUD Arifin Achmad Provinsi Riau. Jurnal Ilmu Kedokteran. 2020;14(2):103–10. https://doi.org/10.26891/JIK.v14i2.2020.103-110
  13. Rajput S, DeMartino R, Mendes B, Sharaf B. Liposuction to Improve Vascular Access in Hemodialysis Patients with Arteriovenous Fistulas. Journal of Vascular Surgery Cases, Innovations and Techniques. 2022;8(4):719–25. https://doi.org/10.1016/j.jvscit.2022.08.014
  14. Siagian Y, Alit DN, Suraidah. Analisis Faktor yang Berhubungan dengan Kepatuhan Pembatasan Asupan Cairan Pasien Hemodialisa. Jurnal Menara Medika. 2021;4(1):71–80
  15. Riskesdas. Laporan Provinsi Sumatera Selatan : Riskesdas. Jakarta: Lembaga Penerbit Badan Penelitian dan Pengembangan Kesehatan; 2018
  16. Oktaveriana D. Gambaran Asupan Energi, Zat Gizi Makro, Natrium, Kalium dan Status Gizi Gagal Ginjal Kronik Pasien Rawat Inap di RSUP Dr. Mohammad Hoesin. Svasta Harena Rafflesia . 2023;2(2):60–72. https://doi.org/10.33088/shr.v2i2.400
  17. Afifah LNA, Asnindari LN, Widiastuti. Hubungan Status Gizi dengan Kualitas Hidup Pasien Gagal Ginjal Kronik yang Menjalani Hemodialisa di RSU PKU Muhammadiyah Bantul. Jurnal Kebidanan dan Keperawatan. 2023;5(1):1–7. https://doi.org/10.33024/mnj.v6i7.14793
  18. Hayati DM, Widiany FL, Nofiartika F. Status Gizi Berdasarkan Dialysis Malnutrition Score (DMS) dengan Kualitas Hidup Pasien Hemodialisis. Jurnal Gizi Klinik Indonesia. 2021;18(1):28–37. https://doi.org/10.22146/ijcn.60778
  19. Nur E, Cintari L. Determinan Kualitas Hidup Penderita Penyakit Gagal Ginjal Kronik yang Menjalani Hemodialisa. Jurnal Skala Husada. 2012;9(1):90–96
  20. Kemenkes. Pedoman Nasional Pelayanan Kedokteran Tata Laksana Ginjal Kronik. Jakarta: Keputusan Menteri Kesehatan Indonesia; 2023
  21. Rosyanti L, Hadi I, Antari I, Ramlah S. Faktor Penyebab Gangguan Psikologis pada Penderita Penyakit Ginjal Kronis yang Menjalani Hemodialisis: Literatur Reviu Naratif. Health Information: Jurnal Penelitian. 2023;15(2):1–19. https://doi.org/10.36990/hijp.v15i2.1102
  22. Zulfikar AN, Koerniawati RD, Perdana F. Hubungan Asupan Zat Gizi Makro Terhadap Status Gizi Pasien Hemodialisa di RSUD dr. Dradjat Prawiranegara. Jurnal Gizi Kerja dan Produktivitas. 2023;4(2):239–248. http://dx.doi.org/10.62870/jgkp.v4i2.24987
  23. Triyono AH, Suandika M, Wibowo TH, Dewi FK. Gambaran Kejadian Komplikasi Intra Hemodialisa pada Pasien Gagal Ginjal Kronik yang Menjalani Hemodialisa di RS TK III 04.06.01 Wijayakusuma Purwokerto. J Nurs Health. 2023;8(1):27–39. https://doi.org/10.52488/jnh.v8i1.209
  24. De Donato A, Buonincontri V, Borriello G, Martinelli G, Mone P. The Dopamine System: Insights between Kidney and Brain. Kidney Blood Press Res. 2022;47:493–505. https://doi.org/10.1159/000522132
  25. Balić A, Vlašić D, Žužul K, Marinović B, Mokos ZB. Omega-3 Versus Omega-6 Polyunsaturated Fatty Acids in the Prevention and Treatment of Inflammatory Skin Diseases. Int J Mol Sci. 2020;21:1–26. https://doi.org/10.3390/ijms21030741
  26. Kot G, Wróbel A, Kuna K, Makówka A, Nowicki M. The Effect of Muscle Cramps During Hemodialysis on Quality of Life and Habitual Physical Activity. Medicina (B Aires). 2024;60(2075):1–12. https://doi.org/10.3390/medicina60122075
  27. Maskouni SJ, Behbahani HB, Alipour M, Javid AZ, Fayazfar F, Tofighzadeh P, et al. Association of Plant and Animal Protein Intake with Sleep Quality and Quality of Life in Hemodialysis Patients: a Multicenter Cross-Sectional Study. Front Nutr. 2024;11:1–13. https://doi.org/0.3389/fnut.2024.1458560
  28. Saitoh M, Ogawa M, Kondo H, Suga K, Takahashi T, Itoh H, et al. Sarcopenic Obesity and Its Association with Frailty and Protein-Energy Wasting in Hemodialysis Patients: Preliminary Data from a Single Center in Japan. Ren Replace Ther. 2019;5(46):1–9. https://doi.org/10.1186/s41100-019-0240-9
  29. Sabatino A, Avesani CM, Regolisti G, Adinolfi M, Benigno G, Delsante M, et al. Sarcopenic obesity and its relation with muscle quality and mortality in patients on chronic hemodialysis. Clinical Nutrition. 2023;42(8):1359–68. https://doi.org/10.1016/j.clnu.2023.06.032
  30. Kim JK, Jeong JH, Song YR, Kim HJ, Lee WY, Kim K Il, et al. Obesity-Related Decrease in Intraoperative Blood Flow is Associated with Maturation Failure of Radiocephalic Arteriovenous Fistula. J Vasc Surg. 2015;62(4):1010–1017. https://doi.org/10.1016/j.jvs.2015.05.008
  31. Zahran A, Ragheb A, Abdullatif AE, Kamal H. Detection of Depression in Patients on Regular Hemodialysis. Menoufia Medical Journal. 2024;37(4):60–7. https://doi.org/10.59204/2314-6788.2927
  32. Ghorbani A, Hayati F, Karandish M, Sabzali S. The Prevalence of Malnutrition in Hemodialysis Patients. J Renal Inj Prev. 2020;9(2):1–6. https://doi.org/10.34172/jrip.2020.15
  33. Adrianto Y, Utari DM. Malnutrition Inflammation in Chronic Kidney Disease Undergoing Hemodialysis in Cipto Mangunkusumo Hospital. Jurnal Gizi Indonesia. 2024;13(1):25–34. https://doi.org/10.14710/jgi.13.1.25-34
  34. Desai MK, Brinton RD. Autoimmune Disease in Women: Endocrine Transition and Risk Across the Lifespan. Front Endocrinol (Lausanne). 2019;10(265):1–19. https://doi.org/10.3389/fendo.2019.00265
  35. Sari LN, Novitasari L, Sutrisna M. Jenis Kelamin Berhubungan dengan Kualitas Hidup Pasien Diabetes Melitus. Jurnal Keperawatan Raflesia. 2024;6(2):91–100. https://doi.org/10.33088/jkr.v6i2.895
  36. Shankar M, Gouri S, Kishan A, Reddy G. Gender Disparity in Maintenance Hemodialysis Units in South India: a Cross-Sectional Observational Study. Frontiers in Nephrology. 2024;4:211–220. https://doi.org/10.3389/fneph.2024.1322003
  37. Nela F, Perangin-angin MA. Perbandingan Kualitas Hidup Pasien Gagal Ginjal Kronik yang Menjalani Hemodialisa di RSA Bandung Berdasarkan Jenis Kelamin. 2025;9(2):377–387. https://doi.org/10.37771/nj.v9i2.1423
  38. Muliani R, Fauziah LA, Sumbara. Komorbiditas dan Lama Menjalani Hemodialisis dengan Kualitas Hidup pada Pasien yang Menjalani Hemodialisis. Window of Health: Jurnal Kesehatan. 2022;5(2):533–44. https://doi.org/10.33096/woh.v5i02.24
  39. Rosyanti L, Hadi I, Ibrahim K. Eksplorasi Perubahan Fisik dan Gejolak Emosional pada Pasien Chronic Kidney Disease yang Menjalani Hemodialisis: Pendekatan Kualitatif. Health Information: Jurnal Penelitian. 2018;10(2):98–112. https://doi.org/10.36990/hijp.v10i2
  40. Cindoğlu Ç, Beyazgül B. Nutritional Status and Anxiety-Depression Relationship in Hemodialysis Patients. Journal of Surgery and Medicine. 2021;5(5):429–32. https://doi.org/10.28982/josam.802547
  41. Rantepadang A. Kadar Hemoglobin dan Lama Hemodialisa terhadap Kualitas Hidup Pasien Gagal Ginjal Kronik yang Menjalani Hemodialisa. Klabat Journal of Nursing. 2022;4(1):36–41. https://doi.org/10.37771/kjn.v4i1.788
  42. Karimah N, Hartanti RD. Gambaran Self Efficacy dan Kualitas Hidup Pada Pasien Yang Menjalani Hemodialisa: Literature Review. Seminar Nasional Kesehatan. 2021;1:446–55. https://doi.org/10.48144/prosiding.v1i.697
  43. Nurfajri QAF, Murtaqib, Widayati N. Literature Review Kejadian Depresi Pasien Gagal Ginjal Kronik yang Menjalani Terapi Hemodialisis. JKEP (Jurnal Keperawatan). 2022;7(2):178–90. https://doi.org/10.32668/jkep.v7i2.849

Last update:

No citation recorded.

Last update:

No citation recorded.