DOI: https://doi.org/10.14710/jnc.v14i3.48314

EFEK DAUN KELOR TERHADAP PROFIL LIPID PADA OBESITAS: TINJAUAN NARATIF

1Department of Nutrition Science, Faculty of Medicine, Universitas Diponegoro, Semarang, Central Java, Indonesia

2Program Studi Ilmu Kedokteran dan Kesehatan, Fakultas Kedokteran, Universitas Diponegoro, Semarang, Jawa Tengah, Indonesia

Received: 6 Dec 2024; Revised: 25 Feb 2025; Accepted: 25 Feb 2025; Available online: 30 Jul 2025; Published: 30 Jul 2025.

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Abstract

ABSTRACT

Background: Obesity is an increasing global health issue and is associated with various metabolic complications, including dyslipidemia. Moringa oleifera, or moringa leaves, are known to have therapeutic potential in the management of this condition.

Objectives: This study aims to evaluate the effects of moringa leaves on the lipid profile of obese patients and to identify the underlying mechanisms of these effects.

Methods: This study uses a literature review approach by collecting data from various national and international articles. The search was conducted through several databases such as Google Scholar, PubMed, and Science Direct using related keywords; “Moringa oleifera”, “Obesity”, “Dyslipidemia”, “Lipid Profile”.

Results: The review results indicate that Moringa oleifera is effective in lowering total cholesterol, LDL, and triglyceride levels, as well as increasing HDL.

Conclusion: Moringa oleifera shows potential as an adjunct therapy in the management of obesity and related complications, providing a safer and more natural alternative to reduce the risk of cardiovascular diseases. Further research is needed to confirm its clinical benefits in humans.


ABSTRAK

Latar belakang: Obesitas menjadi masalah kesehatan global yang meningkat dan berkaitan dengan berbagai komplikasi metabolik, termasuk dislipidemia. Moringa oleifera, atau daun kelor, dikenal memiliki potensi terapeutik dalam pengelolaan kondisi ini.

Tujuan: Penelitian ini bertujuan untuk mengevaluasi efek daun kelor terhadap profil lipid pada pasien obesitas serta mengidentifikasi mekanisme yang mendasari efek tersebut.

Metode: Studi ini menggunakan pendekatan tinjauan naratif dengan mengumpulkan data dari berbagai artikel nasional dan internasional. Pencarian dilakukan melalui beberapa database seperti Google Scholar; PubMed, dan Science Direct dengan kata kunci terkait; “Moringa oleifera”, “Obesitas”, “Dislipidemia”, “Profil lipid”.

Hasil: Hasil tinjauan menunjukkan bahwa Moringa oleifera efektif dalam menurunkan kadar kolesterol total, LDL, dan trigliserida, serta meningkatkan HDL.

Simpulan: Moringa oleifera menunjukkan potensi sebagai terapi tambahan dalam pengelolaan obesitas dan komplikasi terkait, memberikan alternatif yang lebih aman dan alami untuk mengurangi risiko penyakit kardiovaskular. Penelitian lebih lanjut diperlukan untuk memastikan manfaat klinisnya pada manusia.


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Keywords: Moringa oleifera; obesitas; dislipidemia; profil lipid

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