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ANCIENT SCHWANNOMA OF THE RIGHT AXILLARY REGION MIMICKING BREAST MALIGNANCY: A RARE CASE REPORT

*Leonardo Cahyo Nugroho orcid  -  Faculty of Medicine, Universitas Kristen Duta Wacana, Jl. Dr. Wahidin Sudirohusodo No.5-25, Kotabaru, Kec. Gondokusuman, Kota Yogyakarta, Daerah Istimewa Yogyakarta 55224, Indonesia
Lini Sunaryo  -  Department of Pathological Anatomy, Siloam Hospital Yogyakarta, Jl. Laksda Adisucipto No.32-34, Demangan, Kec. Gondokusuman, Kota Yogyakarta, Daerah Istimewa Yogyakarta 55221, Indonesia
Loury Priskila orcid  -  Faculty of Medicine, Universitas Kristen Duta Wacana, Jl. Dr. Wahidin Sudirohusodo No.5-25, Kotabaru, Kec. Gondokusuman, Kota Yogyakarta, Daerah Istimewa Yogyakarta 55224, Indonesia
Ebenezer Devara Yeckopradana orcid  -  Faculty of Medicine, Universitas Kristen Duta Wacana, Jl. Dr. Wahidin Sudirohusodo No.5-25, Kotabaru, Kec. Gondokusuman, Kota Yogyakarta, Daerah Istimewa Yogyakarta 55224, Indonesia
Open Access Copyright 2026 Leonardo Cahyo Nugroho, Lini Sunaryo, Loury Priskila, Ebenezer Devara Yeckopradana
Creative Commons License This work is licensed under a Creative Commons Attribution-NonCommercial-ShareAlike 4.0 International License.

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Abstract

Background: Ancient schwannoma is a rare benign peripheral nerve sheath tumor characterized by degenerative changes, most commonly found in the head, neck, or extremities. Axillary localization, particularly extending to the mammary tail, is extremely rare and may clinically and radiologically mimic breast malignancy due to features commonly associated with malignancy such as an immobile, painless mass with progressive growth and indistinct borders. Case Presentation: A 37-year-old woman presented with a progressively enlarging, firm, immobile right axillary mass accompanied by intermittent paresthesia of the right forearm. Imaging revealed a heterogenous solid mass categorized as BI-RADS IV, raising suspicion for malignancy. Surgical excision was performed, and histopathological examination demonstrated characteristic features of ancient schwannoma, including Antoni A and Antoni B areas with cystic and hemorrhagic degeneration. No malignant transformation was identified. Conclusion: Ancient schwannoma in the axillary region is exceedingly rare and may clinically simulate breast carcinoma. High suspicion and histopathological confirmation are critical to avoid overtreatment. Complete surgical excision remains the definitive treatment with favorable prognosis. Thorough clinical examination, appropriate imaging, and histopathological confirmation must be prioritized to avoid misdiagnosis, especially in cases mimicking malignancy.

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Keywords: Ancient schwannoma; Axillary mass; Breast tumor; Peripheral nerve sheath tumor
Funding: Universitas Kristen Duta Wacana

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