skip to main content

THE ASSOCIATION BETWEEN PLATELET-TO-LYMPHOCYTE RATIO AND BONE MINERAL DENSITY IN REPRODUCTIVE-AGED WOMEN

Nanda Puspa Oktavianingrum  -  Undergraduate Student, Faculty of Medicine, Universitas Diponegoro, Semarang, Indonesia, Indonesia
*Meita Hendrianingtyas  -  Dept of Clinical Pathology, Faculty of Medicine Universitas Diponegoro Semarang, Indonesia
Edward Kurnia Setiawan Limijadi  -  Department of Clinical Pathology, Faculty of Medicine, Universitas Diponegoro, Semarang, Indonesia, Indonesia
Farah Hendara Ningrum  -  Department of Radiology, Faculty of Medicine, Universitas Diponegoro, Semarang, Indonesia, Indonesia
Open Access Copyright 2026 Meita Hendrianingtyas
Creative Commons License This work is licensed under a Creative Commons Attribution-NonCommercial-ShareAlike 4.0 International License.

Citation Format:
Abstract

Background: Bone Mineral Density (BMD) decreases in women aged 40–49 years. Platelet-Lymphocyte Ratio (PLR) is an inflammatory marker involved in the pathophysiology of osteoporosis. Objective: This study aimed to analyze the relationship between PLR and BMD in productive-age women for early osteoporosis risk detection. Method: This analytic observational study with a cross-sectional design included 107 medical records of productive-age women at Diponegoro National Hospital from March to September 2024, selected by consecutive sampling. The relationship between PLR and BMD was analyzed using the Spearman correlation test. Results: The analysis of Spearman correlation test showed that there was no significant relationship between PLR value and BMD value of spine L1 - L4 (p = 0.713; r = -0.036), PLR value and BMD value of left femur neck (p = 0.883; r = 0.014), and PLR value and BMD value of left femur total (p = 0.532; r = 0.061). Conclusion: There was no association between PLR and BMD of the L1–L4 spine, left femur neck, or left femur total; thus, it is not a marker of inflammation.

Keywords: PLR; Bone mineral density; obesity

Article Metrics:

Article Info

Last update:

No citation recorded.

Last update:

No citation recorded.