DOI: https://doi.org/10.14710/dmj.v15i2.53467

CERVICAL CANCER SCREENING OVERVIEW USING LIQUID-BASED CYTOLOGY (LBC) AND HUMAN PAPILLOMAVIRUS (HPV) DETECTION IN YOGYAKARTA

*Auliya Suluk Brilliant Sumpono orcid  -  Pathology Anatomy Department, Dr. Sardjito General Hospital, Faculty of Medicine, Public Health and Nursing, Gadjah Mada University, Indonesia
Faizah Dwi Tirtasari orcid  -  Pathology Anatomy Department, Dr. Sardjito General Hospital, Faculty of Medicine, Public Health and Nursing, Gadjah Mada University, Indonesia
Muhammad Ary Zucha orcid  -  Obsetric and Gynecology Department, Dr. Sardjito General Hospital, Faculty of Medicine, Public Health and Nursing, Gadjah Mada University, Indonesia
Fitriya Ramadhani orcid  -  Histology and Biology Cell Department, Faculty of Medicine, Public Health and Nursing, Gadjah Mada University, Indonesia
Ery Kus Dwianingsih orcid  -  Pathology Anatomy Department, Dr. Sardjito General Hospital, Faculty of Medicine, Public Health and Nursing, Gadjah Mada University, Indonesia
Irianiwati Widodo orcid  -  Pathology Anatomy Department, Dr. Sardjito General Hospital, Faculty of Medicine, Public Health and Nursing, Gadjah Mada University, Indonesia
Open Access Copyright 2026 Auliya Suluk Brilliant Sumpono, Faizah Dwi Tirtasari, Muhammad Ary Zucha, Fitriya Ramadhani, Ery Kus Dwianingsih, Irianiwati Widodo
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Abstract

Background: Screening of cervical cancer persists as a critical approach to persevere as a consequence of the gradually increasing cases and causing high mortality in women, including in Indonesia. The liquid-based cytology (LBC) and human papilloma virus (HPV) is a combination technique which promising and prosperous in detecting cervical cancer. Objective: The study aims to overview the cervical cancer screening results clinically using LBC and HPV testing in Yogyakarta. Methods: secondary data obtained from the medical records of 100 participants who participated in cervical cancer screening. The data collected included sociodemographic, clinical condition overview of the cervix, and results of LBC and HPV tests. Results: The sociodemographic data showed the housewives being a higher occupation percentage (59.8%), and the intrauterine devices (IUD) were the widely used types of contraception (42.3%). The screening was dominantly attended by young age (85.6%). The LBC result showed all of the participants had NILM types (100%), while the HPV results obtained five participants (5.2%) with positive results. In those positive results also discovered the bacterial vaginosis and reactive cellular changes associated with inflammation (p ≤ 0.05). Conclusion: This study concluded that the result of screening cervical cancer in Yogyakarta revealed normal cases in the NILM condition based on the LBC test result. However, the HPV test indicates sensitivity properties from the capability to detect HPV in asymptomatic participants. Thus, the LBC and HPV testing are very suitable and effective to use as a combination for cervical cancer screening strategy.

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Keywords: Cervical cancer; HPV; LBC; NILM; screening
Funding: Dana Hibah Pengabdian Kepada Masyarakat 2023 under contract 4406/UN1/FKKMK.1.4/KAP/PKM/2023

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