ASSOCIATION BETWEEN HbA1C AND TRIGLYCERIDE LEVELS IN DIABETES MELLITUS PATIENTS WITH OBESITY

Abstract

Background: The prevalence of type 2 diabetes mellitus (T2DM) continues to increase, while the obese group has a risk of T2DM seven times greater than the non-obese group. Obesity can also increase triglyceride levels with a significant impact on HbA1c. The relationship between increased HbA1c values and triglyceride levels in T2DM with obese patients needs further discussion. While previous studies have shown correlation between HbA1c and triglycerides, evidence remains scarce in obese with type 2 DM patients in Indonesia. Aim: To analyze the association between HbA1c and triglyceride levels in diabetes mellitus patients with obesity. Methods: This study was an observational analytical with a cross-sectional design conducted on 38 subjects from February – October 2022. The data obtained for this research was secondary data from the medical records of T2DM with obese patients at the Diponegoro National Hospital. The independent variable in this research was HbA1c and the dependent variable was triglyceride levels. The correlation analysis was done using Spearman Rank test. Results: The Spearman Rank’s correlation test results between HbA1c and triglyceride levels in T2DM with obese patients were p<0.001 and coefficient correlation = 0.57. Conclusion: There was a significant positive relationship with a strong correlation between HbA1c and triglyceride levels in T2DM with obese patients. This finding supports the importance of HbA1c and triglyceride monitoring in clinical practice, especially in obese T2DM patients, to manage and reduce long-term cardiovascular risk.