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The Relationship between Chemotherapy Treatment and the Incidence of Seborrheic Dermatitis in Cancer Patients at Dr. Kariadi Hospital

Dhiya Nasywa Ananda Giany  -  Department of Medicine, Universitas Diponegoro, Jl. Prof. Sudarto, SH, Tembalang, Semarang, Indonesia 50275, Indonesia
*Liza Afriliana scopus  -  Department of Dermatology and Venereology, Faculty of Medicine, Universitas Diponegoro, Semarang, Indonesia 50275, Indonesia
Widyawati Widyawati  -  Department of Dermatology and Venereology, Faculty of Medicine, Universitas Diponegoro, Semarang, Indonesia 50275, Indonesia
Buwono Puruhito scopus  -  Department of Dermatology and Venereology, Faculty of Medicine, Universitas Diponegoro, Semarang, Indonesia 50275, Indonesia

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Abstract

Background: Seborrheic dermatitis is a chronic inflammation of sebaceous gland-rich areas in the form of reddish, well-demarcated plaques and yellowish flaking scabs that can interfere with the patient's comfort and quality of life. Immune system suppression such as chemotherapy in cancer patients is thought to be one of the contributing factors. When seborrheic dermatitis is caused by chemotherapy, it will add to the suffering of patients both in terms of quality of life and treatment costs. Objective: To find out the difference in the incidence of seborrheic dermatitis in cancer patients who are undergoing chemotherapy and cancer patients who are not receiving chemotherapy. Methods: This study was an analytic observational study with a cross-sectional design. The study subjects were 40 people who were cancer patients at Dr. Kariadi Hospital who were selected by consecutive sampling method. The questionnaire used to determine the details of chemotherapy actions and the incidence of seborrheic dermatitis made by the author has been tested validity. Data processing used Chi Square or Fisher Exact analysis test and multivariate logistic regression test. Results: There was 73.3% incidence of seborrheic dermatitis in patients who were undergoing chemotherapy, 26.7% incidence of seborrheic dermatitis in patients who were not. The Chi Square test found a significant association between chemotherapy treatment and the incidence of seborrheic dermatitis with p = 0.022. The bivariate analysis test did not show a significant relationship between age, gender, and personal hygiene with the incidence of seborrheic dermatitis. There was a significant and additive relationship between chemotherapy treatment and personal hygiene with the incidence of seborrheic dermatitis. Conclusion: Chemotherapy treatment is a risk factor for Seborrheic Dermatitis. Age, gender and personal hygiene are not independent risk factors for seborrheic dermatitis. Poor personal hygiene is also a risk factor when combined with chemotherapy.

Keywords: Age, Chemotherapy, Gender, Personal hygiene, Seborrheic dermatitis
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Keywords: Age; Chemotherapy; Gender; Personal hygiene; Seborrheic dermatitis

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