slot gacor slot gacor hari ini slot gacor 2025 demo slot pg slot gacor slot gacor
Histopathological Study of Sinonasal and Nasopharyngeal Lesions in Sumber Waras Hospital Jakarta from 2017-2023 | Dewi | Jurnal Kedokteran Diponegoro (Diponegoro Medical Journal)

DOI: https://doi.org/10.14710/dmj.v13i4.45913

Histopathological Study of Sinonasal and Nasopharyngeal Lesions in Sumber Waras Hospital Jakarta from 2017-2023

Yunita Dewi  -  Faculty of Medicine, Universitas Tarumanagara, Jl. Letjen S. Parman No. 1, Jakarta, 11440, Indonesia
*Sony Sugiharto orcid scopus  -  Universitas Tarumanagara, Indonesia

Citation Format:
Abstract

Background: Various non-neoplastic and neoplastic lesions arise from the sinonasal tract and nasopharynx. Polyps are the most frequently reported sinonasal lesions, with a prevalence of 2 %. Nasopharyngeal carcinoma is a common malignancy in Indonesia, with 19.943 new cases. Histopathological examination is the gold standard for diagnosis because management and prognosis vary among different lesions. Objective: The aim is to determine the incidence of various non-neoplastic and neoplastic lesions and to study the histopathological features with regard to age and gender. Methods: This study was a descriptive observational study with a cross-sectional design. The sample was retrieved from the histopathological records in Sumber Waras Hospital Jakarta from February 2017 to December 2023. The inclusion criteria were all patients with sinonasal or nasopharyngeal lesions that have been biopsied and then done histopathological examination at Sumber Waras Hospital Jakarta. The exclusion criteria were incomplete data and patients with histopathological diagnoses of necrotic tissue and inflammation. The sample consisted of 73 patients with a total of 76 cases, as 3 patients had multiple diagnoses. The data collected were later analyzed with SPSS software. Results: Among 73 patients, 54 were males and 19 were females. A maximum number of cases were diagnosed in the age group of 51-60. Among 43 sinonasal lesions, 25 (58,2%) were non-neoplastic and 18 (42%) were neoplastic lesions. Inflammatory polyps (42%) were the most common among the sinonasal lesions. Of 33 nasopharyngeal lesions, there were 2 (6,1%) non-neoplastic and 31 (93,9%) neoplastic lesions. The majority of these were of nasopharyngeal carcinoma (84,8%). Conclusion: Histopathological examination is essential for diagnosing and classifying sinonasal and nasopharyngeal lesions.

Fulltext View|Download
Keywords: histopathological examination; nasopharynx; non-neoplastic; neoplastic; sinonasal

Article Metrics:

Article Info
Section: Original Articles
Language : EN
Recent articles
Comparison of Intravenous Indocyanine-Green and Inflation-Deflation Method in Lung Segmentectomy: A Meta-Analysis The Effect of Moringa Leaves Extracts on MDA Level in Male Mice Exposed to Electromagnetic Radiation of Mobile Phones Recent Updates of Stem Cell Therapy in Spontaneous Intracerebral Haemorrhage Patients: A Review Article More recent articles
  1. Bhattacharya J, Goswami BK, Banerjee A, Bhattacharyya R, Chakrabarti I, Giri A. A clinicopathological study of masses arising from sinonasal tract and nasopharynx in north Bengal population with special reference to neoplasms. Egyptian Journal of Otolaryngology. 2015 Apr 1;31(2):98–104
  2. Srikanth S, Rajitha J. Spectrum of Histopathological Study of Lesions of Nasal cavity and Paranasal Sinuses – A two Years Study. Scholars Journal of Applied Medical Sciences. 2021 Mar 10;9(3):378–80
  3. Jaison J, Tekwani DT. Histopathological Lesions of Nasal Cavity, Paranasal Sinuses and Nasopharynx. Ann Appl Biosci. 2015;2(2):A40–6
  4. Surange D, Goswami HM, Parikh U, Pratap T, Kourav S. Histopathological Study of Sinonasal and Nasopharyngeal Lesions in a Tertiary Care Hospital Over the Period of 2 Years. International Journal of Contemporary Pathology. 2020;6(1):11–6
  5. Burdak H, Harshvardhan R, Sehra R, Meena R. A Descriptive Study of Clinical, Radiological, and Histopathological Correlation of Sinonasal Masses. Int J Sci Study. 2021;8(12):26–31
  6. Lucidi D, Cantaffa C, Miglio M, Spina F, Alicandri Ciufelli M, Marchioni A, et al. Tumors of the Nose and Paranasal Sinuses: Promoting Factors and Molecular Mechanisms—A Systematic Review. Vol. 24, International Journal of Molecular Sciences. MDPI; 2023
  7. Daulay ER. International Journal of Nasopharyngeal Carcinoma. Talenta Publisher. 2021;3(1):31–5
  8. Adham M, Kurniawan AN, Muhtadi AI, Roezin A, Hermani B, Gondhowiardjo S, et al. Nasopharyngeal carcinoma in indonesia: Epidemiology, incidence, signs, and symptoms at presentation. Chin J Cancer. 2012;31(4):185–96
  9. World Health Organization. World cancer statistics. International Agency For Research on Cancer [Internet]. 2020. Available from: https://gco.iarc.fr/today/data/factsheets/populations/900-world-fact-sheets.pdf
  10. World Health Organization. Indonesia cancer statistics. International Agency For Research on Cancer. 2020; Available from: https://gco.iarc.fr/today/data/factsheets/populations/360-indonesia-fact-sheets.pdf
  11. Regmi S, Ghosh A, Magar DG, Thapa S, Koirala KP, Talwar OP. Histopathology of sinonasal and nasopharyngeal neoplastic lesions in a tertiary care center of western nepal: A descriptive cross-sectional study. Journal of the Nepal Medical Association. 2021 Jul 1;59(239):657–62
  12. Garg D, Mathur K. Clinico-pathological study of space occupying lesions of nasal cavity, paranasal sinuses and nasopharynx. Journal of Clinical and Diagnostic Research. 2014 Nov 20;8(11):FC04–7
  13. Patel U, Chauhan H, Patel N. Clinicopathological study and management of masses in the sinonasal cavity and nasopharynx: a case series of 42 cases. Egyptian Journal of Otolaryngology. 2023 Dec 1;39(1)
  14. Sarumathy DrG, Saraswathy DrM, Devi DrEP. Spectrum of mass lesions in nasal cavity, Paranasal Sinuses and Nasopharynx: A Histopathological study of 115 cases. International Journal of Clinical and Diagnostic Pathology. 2021 Apr 1;4(2):136–42
  15. Chauhan JPS, Gupta R, Kumar A. Nasal polyps and its histopathological classification: A retrospective study. Asian J Med Sci. 2023 Aug 1;14(8):164–9
  16. Mohapatra D, Mohapatra AS, Swain SK. Clinico-Histopathological Spectrum of Sinonasal and Nasopharyngeal Lesions- A Two Years Study at a Tertiary Care Hospital in Eastern India. Journal of Evidence Based Medicine and Healthcare. 2020 Aug 17;7(33):1645–51
  17. Vare AA, Vare RA, Gurma B. Histopathological lesions of nose, paranasal sinuses and nasopharynx at a tertiary care centre. MedPulse International Journal of ENT [Internet]. 2018;8(2):37–41. Available from: https://medpulse.in/ENT/html_8_2_4.php
  18. Bundela A, Mitra S. The Histopathological study of Lesions of the Nasal Cavity, Paranasal Sinuses and Nasopharynx in Eastern UP, India. Tropical Journal of Pathology and Microbiology. 2022;8(5)
  19. Guleria TC, Mohindroo S, Mohindroo NK, Azad RK, Kumar A. Histopathological profile of nasal cavity, paranasal sinuses, and nasopharyngeal masses in hill state of Himachal Pradesh, India. Clinical Rhinology. 2017;10(2):93–8
  20. Korata R, Veeragandham S, Yarlagadda KB. Histopathological Analysis of Sinonasal and Nasopharyngeal Lesions- A Retrospective Study. NATIONAL JOURNAL OF LABORATORY MEDICINE. 2023;
  21. Gedam PK, Chawhan SM, Chawhan SS, Pandhare ML. Histopathological Study of Lesions of Nasal Cavity and Paranasal Sinuses. Journal of Medical Sciences and Health. 2022 Jun 15;8(1):65–72
  22. Jagannadham RP, Latchupatula L, Ponnada S, Lalam N, Gudipudi R, Atla B. Histopathological Study of Lesions of the Nasal Cavity, Paranasal Sinuses and Nasopharynx in a Tertiary Care Centre, Visakhapatnam over a Period of 2 Years. Journal of Evidence Based Medicine and Healthcare. 2021 Aug 16;8(33):3054–9
  23. Shetty A, Kulkarni A, Pathak P. Histopathological study of lesions of nasal cavity and paranasal sinuses. Indian Journal of Pathology and Oncology. 2020 Mar 28;7(1):88–93
  24. Shirazi N, Bist SS, Selvi TN, Harsh M. Spectrum of sinonasal tumors: A 10-year experience at a tertiary care Hospital in North India. Oman Med J. 2015;30(6):435–40
  26. Vartak UC, Sarnaik AG, Vartak S, Pathan F. Spectrum of histopathological lesions of nose and paranasal sinuses: A 5-year study. JMS - Journal of Medical Society. 2020;34(3):128–38
  27. Narvey VP, Saxena S, Saluja M. Clinico-histopathological Features of Sinonasal Lesions: An Experience from a Tertiary Care Hospital, Central India. INTERNATIONAL JOURNAL OF ANATOMY RADIOLOGY AND SURGERY. 2022;
  28. Kumari S, Pandey S, Verma M, Rana AK, Kumari S. Clinicopathological Challenges in Tumors of the Nasal Cavity and Paranasal Sinuses: Our Experience. Cureus. 2022 Sep 13;
  29. Ahmad N, Khan S, Hassan MDJ, Jetley S. Histopathological profile of sinonasal lesions with brief clinical correlation: experience in a tertiary care centre. Tropical Journal of Pathology & Microbiology. 2017;3(4):382–9
  30. Patel PR, Neb V, Bhagat V, Rupareliya N, Gandhi N. Spectrum of neoplastic sino-nasal lesions at tertiary care centre. Indian Journal of Pathology and Oncology. 2020 Mar 28;7(1):104–8

Last update:

No citation recorded.

Last update:

No citation recorded.