DOI: https://doi.org/10.14710/dmj.v12i6.40838

Emerging Frontiers in Cardiovascular Diagnostics: A State-of-the-Art Review

*Roy Novri Ramadhan orcid  -  Medical Program, Faculty of Medicine, Universitas Airlangga, 60132 Surabaya, Indonesia, Indonesia
Dewi Ratna Sari  -  Department of Anatomy, Histology, & Pharmacology, Faculty of Medicine, Universitas Airlangga 60132 Surabaya, Indonesia, Indonesia
Muh Akram  -  Medical Program, Faculty of Medicine, Universitas Airlangga, 60132 Surabaya, Indonesia, Indonesia
Farhan Nurdiansyah  -  Medical Program, Faculty of Medicine, Universitas Airlangga, 60132 Surabaya, Indonesia, Indonesia

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Abstract

Background: The cardiovascular diagnostic landscape is rapidly evolving, with novel and advanced techniques and technologies continually emerging. Detection, monitoring, and management of cardiovascular diseases (CVDs) are quickly changing, which are leading mortality cause globally. Objective:This review aims to provide a comprehensive and up-to-date assessment of the current cardiovascular diagnostic modalities. It seeks to elucidate novel and promising technologies, address their advantages, limitations, and potential integration into clinical practice. Methods: This literature review discusses the recent cardiovascular diagnostics which were obtained from various sources such as PubMed, EMBASE, and Web of Science for articles published in the last decade. Results: The review identified vital emerging frontiers in cardiovascular diagnosis, including advancements in multi-modal imaging (such as PET-MRI), novel biomarkers, artificial intelligence applications, and the growing utility of wearable and remote monitoring technologies. Conclusion: Emerging techniques integration inroutine clinical practice requires careful consideration of their advantages and potential for improving patient outcomes. The review highlights the pressing need for continued research and guideline to ensure these innovations realize their full potential for the future of cardiovascular medicine.

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Keywords: Cardiovascular, diagnostics, novel, technology.

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Section: Original Articles
Language : EN
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  1. Dornbush S. Physiology, heart sounds [Internet]. StatPearls - NCBI Bookshelf. 2023. Available from: https://www.ncbi.nlm.nih.gov/books/NBK541010/
  2. Diagnosis and screening for cardiovascular conditions [Internet]. Johns Hopkins Medicine. Available from: https://www.hopkinsmedicine.org/health/treatment-tests-and-therapies/diagnosis-and-screening-for-cardiovascular-conditions#:~:text=Cardiovascular%20diagnostic%20and%20screening%20tests,and%20whether%20there%20are%20tumors
  3. Roguin A. Rene Theophile Hyacinthe Laennec (1781-1826): The Man Behind the Stethoscope. Clinical Medicine & Research [Internet]. 2006 Sep 1;4(3):230–5. Available from: https://doi.org/10.3121/cmr.4.3.230
  4. History of the Sphygmomanometer | American Diagnostic Corporation [Internet]. Available from: https://www.adctoday.com/learning-center/about-sphygmomanometers/history-sphygmomanometer
  5. Barold SS. Willem Einthoven and the birth of clinical electrocardiography a hundred years ago. Cardiac Electrophysiology Review [Internet]. 2003 Jan 1;7(1):99–104. Available from: https://doi.org/10.1023/a:1023667812925
  6. Right heart cardiac catheterization [Internet]. PubMed. 2023. Available from: https://pubmed.ncbi.nlm.nih.gov/32491336/
  7. Secretariat MA. Noninvasive Cardiac Imaging Technologies for the Diagnosis of Coronary Artery Disease: A Summary of Evidence-Based Analyses [Internet]. PubMed Central (PMC). 2010. Available from: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3377536/
  8. World Health Organization: WHO. Cardiovascular diseases (CVDs). www.who.int [Internet]. 2021 Jun 11; Available from: https://www.who.int/news-room/fact-sheets/detail/cardiovascular-diseases-(vcds)
  9. Noncommunicable diseases: A scoping review focus on the context of India. NCBI [Internet]. 2023; Available from: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10127498/
  10. Heart Disease and Stroke Statistics Update Fact Sheet. American Heart Association [Internet]. 2023; Available from: https://professional.heart.org/-/media/PHD-Files-2/Science-News/2/2023-Heart-and-Stroke-Stat-Update/2023-Statistics-At-A-Glance-final_1_17_23.pdf
  11. Heart Disease and Stroke Statistics - 2023 update [Internet]. professional.heart.org. Available from: https://professional.heart.org/en/science-news/heart-disease-and-stroke-statistics-2023-update#:~:text=Cardiovascular%20disease%20(CVD)%20remains%20as,in%20lost%20productivity%2Fmortality)
  12. Di Franco A, Ohmes LB, Gaudino M, Rong LQ, Girardi LN, Sarullo FM, et al. Serendipity and innovation: history and evolution of transthoracic Echocardiography. Journal of Thoracic Disease [Internet]. 2017 Apr 1;9(S4):S257–63. Available from: https://doi.org/10.21037/jtd.2017.03.90
  13. Maleki M. The evolutionary development of Echocardiography [Internet]. PubMed Central (PMC). 2012. Available from: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3565194/
  14. Maganti K, Rigolin VH, Sarano ME, Bonow RO. Valvular heart disease: diagnosis and management. Mayo Clinic Proceedings [Internet]. 2010 May 1;85(5):483–500. Available from: https://doi.org/10.4065/mcp.2009.0706
  15. Professional CCM. Echocardiogram: transthoracic (TTE) [Internet]. Cleveland Clinic. Available from: https://my.clevelandclinic.org/health/diagnostics/13477-echocardiogram-transthoracic-tte
  16. Manual of 3D Echocardiography [Internet]. Springer eBooks. 2017. Available from: https://doi.org/10.1007/978-3-319-50335-6
  17. Bellenger NG. Comparison of left ventricular ejection fraction and volumes in heart failure by Echocardiography, radionuclide ventriculography, and cardiovascular magnetic resonance. Are they interchangeable? European Heart Journal [Internet]. 2000 Aug 15;21(16):1387–96. Available from: https://doi.org/10.1053/euhj.2000.2011
  18. Dorosz JL, Lezotte DC, Weitzenkamp D, Allen LA, Salcedo EE. Performance of 3-Dimensional Echocardiography in measuring left ventricular volumes and ejection fraction. Journal of the American College of Cardiology [Internet]. 2012 May 1;59(20):1799–808. Available from: https://doi.org/10.1016/j.jacc.2012.01.037
  19. Kwon SH, Gopal AS. 3D and 4D Ultrasound: Current Progress and Future Perspectives. Current Cardiovascular Imaging Reports [Internet]. 2017 Nov 10;10(12). Available from: https://doi.org/10.1007/s12410-017-9440-2
  20. Counseller Q, Aboelkassem Y. Recent technologies in cardiac imaging. Frontiers in Medical Technology [Internet]. 2023 Jan 10;4. Available from: https://doi.org/10.3389/fmedt.2022.984492
  21. Sun Z, Choo G, Ng KH. Coronary CT angiography: current status and continuing challenges. British Journal of Radiology [Internet]. 2012 May 1;85(1013):495–510. Available from: https://doi.org/10.1259/bjr/15296170
  22. Goo HW, Goo JM. Dual-Energy CT: the new horizon in medical imaging. Korean Journal of Radiology [Internet]. 2017 Jan 1;18(4):555. Available from: https://doi.org/10.3348/kjr.2017.18.4.555
  23. Another notable advancement is the Fractional Flow Reserve CT (FFR-CT), a noninvasive method measuring coronary arteries' blood flow and refining blockage assessments. - Google Search [Internet]. Available from: https://www.google.com/search?q=Another+notable+advancement+is+the+Fractional+Flow+Reserve+CT+(FFR-CT)%2C+a+non-invasive+method+measuring+coronary+arteries+blood+flow+and+refining+blockage+assessments.&oq=Another+notable+advancement+is+the+Fractional+Flow+Reserve+CT+(FFR-CT)%2C+a+non-invasive+method+measuring+coronary+arteries+blood+flow+and+refining+blockage+assessments.&gs_lcrp=EgZjaHJvbWUyBggAEEUYOdIBBzMzOWowajSoAgCwAgA&sourceid=chrome&ie=UTF-8
  24. Alizadeh LS, Vogl TJ, Waldeck S, Overhoff D, D’Angelo T, Martin SS, et al. Dual-Energy CT in Cardiothoracic Imaging: current developments. Diagnostics [Internet]. 2023 Jun 19;13(12):2116. Available from: https://doi.org/10.3390/diagnostics13122116
  25. Since Magnetic Resonance Imaging (MRI) 7T scanners launched offered the potential to acquire clearer and more detailed cardiovascular images than ever before. The elevated magnetic field strength of 7T scanners provides superior image clarity compared to their 1.5T and 3T counterparts and significantly enhanced image resolution. This makes them particularly adept at capturing detailed images of the cardiac muscle, intricate - Google Search [Internet]. Available from: https://www.google.com/search?q=Since+Magnetic+Resonance+Imaging+(MRI)+7T+scanners+launched+offering+the+potential+to+acquire+clearer+and+more+detailed+cardiovascular+images+than+ever+before.+The+elevated+magnetic+field+strength+of+7T+scanners+provides+superior+image+clarity%2C+compared+to+their+1.5T+and+3T+counterparts%2C+provides+significantly+enhanced+image+resolution.+This+makes+them+particularly+adept+at+capturing+detailed+images+of+the+cardiac+muscle%2C+intricat&oq=Since+Magnetic+Resonance+Imaging+(MRI)+7T+scanners+launched+offering+the+potential+to+acquire+clearer+and+more+detailed+cardiovascular+images+than+ever+before.+The+elevated+magnetic+field+strength+of+7T+scanners+provides+superior+image+clarity%2C+compared+to+their+1.5T+and+3T+counterparts%2C+provides+significantly+enhanced+image+resolution.+This+makes+them+particularly+adept+at+capturing+detailed+images+of+the+cardiac+muscle%2C+intricat&gs_lcrp=EgZjaHJvbWUyBggAEEUYOdIBBzc1MGowajmoAgCwAgA&sourceid=chrome&ie=UTF-8
  26. Lee SE, Nguyen C, Xie Y, Deng Z, Zhou Z, Li D, et al. Recent advances in cardiac magnetic resonance imaging. Korean Circulation Journal [Internet]. 2019 Jan 1;49(2):146. Available from: https://doi.org/10.4070/kcj.2018.0246
  27. Radiological Society of North America (RSNA) and American College of Radiology (ACR). Catheter angiography [Internet]. Radiologyinfo.org. Available from: https://www.radiologyinfo.org/en/info/angiocath
  28. Digital Subtraction Angiography (DSA) Scan | Gleneagles Hospital [Internet]. GEH. Available from: https://www.gleneagles.com.sg/tests-treatments/digital-subtraction-angiography#:~:text=Digital%20subtraction%20angiography%20(DSA)%20is,%2C%20computerised%20X%2Dray%20machines
  29. The Texas Heart Institute. Optical Coherence Tomography | The Texas Heart Institute [Internet]. The Texas Heart Institute. 2018. Available from: https://www.texasheart.org/heart-health/heart-information-center/topics/optical-coherence-tomography/#:~:text=OCT%20uses%20near%2Dinfrared%20light,and%20some%20of%20it%20scatters
  30. National Academies Press (US). Single photon emission computed tomography [Internet]. Mathematics and Physics of Emerging Biomedical Imaging - NCBI Bookshelf. 1996. Available from: https://www.ncbi.nlm.nih.gov/books/NBK232492/
  31. Radioisotopes in Medicine | Nuclear Medicine - World Nuclear Association [Internet]. Available from: https://world-nuclear.org/information-library/non-power-nuclear-applications/radioisotopes-research/radioisotopes-in-medicine.aspx
  32. Karatzia L, Aung N, Aksentijevic D. Artificial intelligence in cardiology: Hope for the future and power for the present. Frontiers in Cardiovascular Medicine [Internet]. 2022 Oct 13;9. Available from: https://doi.org/10.3389/fcvm.2022.945726
  33. Types [Internet]. Stanford Health Care. 2020. Available from: https://stanfordhealthcare.org/medical-tests/e/echocardiogram/types.html
  34. New technology can help patients with heart disease | Banner [Internet]. Available from: https://www.bannerhealth.com/healthcareblog/better-me/coronary-artery-disease-and-heartflow#:~:text=%E2%80%9CHeartFlow%20is%20a%20new%20technology,based%20on%20the%20images%20gathered.%E2%80%9D
  35. Kiamanesh O, Toma M. The State of the Heart Biopsy: A Clinical Review. CJC Open [Internet]. 2021 Apr 1;3(4):524–31. Available from: https://doi.org/10.1016/j.cjco.2020.11.017
  36. Oluleye O, Folsom AR, Nambi V, Lutsey PL, Ballantyne CM. Troponin T, B-type natriuretic peptide, C-reactive protein, and cause-specific mortality. Annals of Epidemiology [Internet]. 2013 Feb 1;23(2):66–73. Available from: https://doi.org/10.1016/j.annepidem.2012.11.004
  37. Deng Z, Guo L, Chen X, Wu W. Smart wearable systems for health monitoring. Sensors [Internet]. 2023 Feb 23;23(5):2479. Available from: https://doi.org/10.3390/s23052479
  38. Prieto-Avalos G, Cruz-Ramos NA, Alor-Hernández G, Sánchez-Cervantes JL, Rodríguez-Mazahua L, Guarneros-Nolasco LR. Wearable Devices for Physical Monitoring of heart: a review. Biosensors [Internet]. 2022 May 2;12(5):292. Available from: https://doi.org/10.3390/bios12050292
  39. Velasco O, Beckett MQ, James AW, Loehr MN, Lewis TG, Hassan T, et al. Real-Time Three-Dimensional Echocardiography: Characterization of Cardiac Anatomy and Function—Current Clinical Applications and Literature review update. BioResearch Open Access [Internet]. 2017 Dec 1; Available from: https://doi.org/10.1089/biores.2016.0033
  40. Kim H, Song J, Kim S, Lee S, Park Y, Lee S, et al. Recent Advances in multiplexed wearable sensor Platforms for Real-Time Monitoring Lifetime Stress: a review. Biosensors [Internet]. 2023 Apr 11;13(4):470. Available from: https://doi.org/10.3390/bios13040470

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