HUBUNGAN PAPARAN TOLUENE DENGAN GANGGUAN FUNGSI HATI PADA PEKERJA BAGIAN PENGECATAN SEBUAH INDUSTRI KAROSERI DI MAGELANG

Mirror Sabda Mahendra Amien; Ari Suwondo; Siswi Jayanti

doi:10.14710/jkm.v3i1.11458

DOI: https://doi.org/10.14710/jkm.v3i1.11458

HUBUNGAN PAPARAN TOLUENE DENGAN GANGGUAN FUNGSI HATI PADA PEKERJA BAGIAN PENGECATAN SEBUAH INDUSTRI KAROSERI DI MAGELANG

*Mirror Sabda Mahendra Amien - , Indonesia

Ari Suwondo - , Indonesia

Siswi Jayanti - , Indonesia

Published: 2 Mar 2015.

BibTex Citation Data :

@article{JKM11458,
    author = {Mirror Mahendra Amien and Ari Suwondo and Siswi Jayanti},
    title = {HUBUNGAN PAPARAN TOLUENE DENGAN GANGGUAN FUNGSI HATI PADA PEKERJA BAGIAN PENGECATAN SEBUAH INDUSTRI KAROSERI DI MAGELANG},
    journal = {Jurnal Kesehatan Masyarakat},
  volume = {3},
    number = {1},
    year = {2015},
    keywords = {Toluene, Liver Dysfunction, ALT, AST},
    abstract = {  Toluene was a volatile organic compound (VOC) or organic chemicals that very easy to vapor in room temperature. Toluene that fat soluble so easily accumulated in organs that contain lots of fat, one of them was liver. Liver was the main organ in the metabolism of toxic substances including toluene. Toluene metabolism produces reactive oxygen species (ROS) that was free radicals can damage cells. Indicator that used to detect the presence of liver damage was the levels of alanine aminotransferase (ALT) and aspartate aminotransferase (AST) in the blood. The purpose of this study was to determine the association between toluene exposure with liver dysfunction in workers painting. This research used analytic observational method with cross-sectional approach. The population of of this study was 26 people. Sampling technique used total sampling. Analysis of association between toluene concentration with levels of ALT and AST, working period with AST used Spearman Rank test, work period with ALT levels used Pearson Product Moment. The results of this current research showed no association between toluene concentration with levels of ALT and AST in the blood, there is a association between work period with ALT levels and there is no association between work period with AST levels in the blood. Advice given that workers should wear a mask a respiratory purifiying when did the painting to reduce the toluene exposure .    },
   issn = {2356-3346},   pages = {395--404}  doi = {10.14710/jkm.v3i1.11458},
    url = {https://ejournal3.undip.ac.id/index.php/jkm/article/view/11458}
}

Citation Format:

Abstract

Toluene was a volatile organic compound (VOC) or organic chemicals that very easy to vapor in room temperature. Toluene that fat soluble so easily accumulated in organs that contain lots of fat, one of them was liver. Liver was the main organ in the metabolism of toxic substances including toluene. Toluene metabolism produces reactive oxygen species (ROS) that was free radicals can damage cells. Indicator that used to detect the presence of liver damage was the levels of alanine aminotransferase (ALT) and aspartate aminotransferase (AST) in the blood. The purpose of this study was to determine the association between toluene exposure with liver dysfunction in workers painting. This research used analytic observational method with cross-sectional approach. The population of of this study was 26 people. Sampling technique used total sampling. Analysis of association between toluene concentration with levels of ALT and AST, working period with AST used Spearman Rank test, work period with ALT levels used Pearson Product Moment. The results of this current research showed no association between toluene concentration with levels of ALT and AST in the blood, there is a association between work period with ALT levels and there is no association between work period with AST levels in the blood. Advice given that workers should wear a mask a respiratory purifiying when did the painting to reduce the toluene exposure.

Fulltext View|Download

Keywords: Toluene, Liver Dysfunction, ALT, AST

Article Metrics:

Article Info

Section: Keselamatan dan Kesehatan Kerja

In Vol 3, No 1 (2015): JANUARI

Recent articles

Evaluasi Pelaksanaan Sosialisasi Program Jaminan Kesehatan Nasional dari Aspek Struktur dan Interaksi Sosialisasi Pada Bulan Januari-Maret 2014 di Puskesmas Ngesrep Semarang SOSIALISASI PROGRAM JAMINAN KESEHATAN NASIONAL OLEH TIM BADAN PENYELENGGARA JAMINAN SOSIAL KEPADA PASIEN DI RSUD RAA SOEWONDO KABUPATEN PATI HUBUNGAN FAKTOR RIWAYAT EFEK SAMPING, AKSES PELAYANAN DAN TOKOH PANUTAN DENGAN KEIKUTSERTAAN SEBAGAI AKSEPTOR KONTRASEPSI TUBEKTOMI DI KELURAHAN MANGUNSARI KOTA SALATIGA HUBUNGAN BEBERAPA KELUHAN PUS DENGAN LAMA PEMAKAIAN IUD PADA AKSEPTOR AKTIF IUD DI KECAMATAN MIJEN KOTA SEMARANG TAHUN 2013 STUDI LABORATORIUM UJI TOKSISITAS ISOLAT Bacillus thuringiensisisraelensis DALAM MEDIA AIR PERASAN SINGKONG TERHADAP LARVA NYAMUK Aedes aegypti SURVEI KEBERADAAN FORMALIN PADA TELUR AYAM RAS DI PASAR TRADISIONAL INDUK DAN PASAR MODERN KAWASAN KOTA SEMARANG FAKTOR-FAKTOR YANG MEMPENGARUHI KONSUMSI MAKAN BUAH DAN SAYUR PADA ANAK PRA SEKOLAH PAUD TK SAPTA PRASETYA KOTA SEMARANG PENGARUH PEMBERIAN EKSTRAK SECANG (Caesalpinnia sappan L.) TERHADAP KUALITAS SENSORIS DAN MIKROBIOLOGIS KUE BOLU KUKUS TAHUN 2014 Evaluasi Pemenuhan Permenaker No.04/MEN/1980 dan SKEP/100/xi/1985 Terhadap Alat Pemadam Api Ringan di PT. Angkasa Pura I Bandar Udara Ahmad Yani Semarang HUBUNGAN PAPARAN DEBU ASBES TERHADAP KAPASITAS VITAL PARU PADA PEKERJA PEMBUAT ASBES DI AREA FINISHING LINE PT. X JAWA TENGAH HUBUNGAN FAKTOR LINGKUNGAN FISIK RUMAH DENGAN KEJADIAN PNEUMONIA PADA BALITA (Studi Kasus di Wilayah Kerja Puskesmas Candi Lama Kecamatan Candisari Kota Semarang) HUBUNGAN KUALITAS LINGKUNGAN FISIK RUMAH DAN PERILAKU KESEHATAN DENGAN KEJADIAN TB PARU DI WILAYAH KERJA PUSKESMAS GONDANGLEGI KECAMATAN GONDANGLEGI KABUPATEN MALANG FAKTOR-FAKTOR YANG BERHUBUNGAN DENGAN PERILAKU WANITA PEKERJA SEKS (WPS) UNTUK MELAKUKAN VCT DI LOKALISASI TEGAL PANAS KABUPATEN SEMARANG PERILAKU WANITA PEKERJA SEKSUAL (WPS) DALAM MELAKUKAN SKRINING INFEKSI MENULAR SEKSUAL (IMS) DI LOKALISASI TEGAL PANAS KABUPATEN SEMARANG More recent articles

Last update:

No citation recorded.

Last update:

No citation recorded.

The Authors submitting a manuscript do so on the understanding that if accepted for publication, copyright of the article shall be assigned to Jurnal Kesehatan Masyarakat (JKM, p-ISSN: 2715-5617, e-ISSN:2356-3346) and Faculty of Public Health, Diponegoro University as the publisher of the journal. Copyright encompasses the rights to reproduce and deliver the article in all form and media, including reprints, photographs, microfilms, and any other similar reproductions, as well as translations.

JKM journal and Faculty of Public Health, Diponegoro University, the Editors and the Advisory Editorial Board make every effort to ensure that no wrong or misleading data, opinions or statements be published in the journal. In any way, the contents of the articles and advertisements published in the JKM journal are the sole and exclusive responsibility of their respective authors and advertisers.

The Copyright Transfer Form can be downloaded here: [Copyright Transfer Form JKM journal]
The copyright form should be signed originally and send to the Editorial Office in the form of original mail or scanned document to jkm@live.undip.ac.id.