DOI: https://doi.org/10.14710/dmj.v14i5.49050

DIFFERENTIATING APPENDICITIS TYPES: THE ROLE OF NEUTROPHIL SUBTYPES

*Helman Kurniadi orcid  -  Universitas Adiwangsa Jambi, Indonesia
Timbul Partogi Haposan Simorangkir  -  1. Gatot Soebroto Army Central Hospital, Indonesia , Indonesia
Open Access Copyright 2025 Helman Kurniadi, Timbul Partogi Haposan Simorangkir
Creative Commons License This work is licensed under a Creative Commons Attribution-NonCommercial-ShareAlike 4.0 International License.

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Abstract

Background: Recent studies have highlighted the significance of inflammatory markers in diagnosing appendicitis; however, the specific roles of stab and segmented neutrophils in assessing disease severity remain poorly understood. Objective: This study aims to analyze the relationship between the types of appendicitis (complicated and uncomplicated) and neutrophil counts (stab and segmented), along with demographic variables such as age and gender, to evaluate their diagnostic significance. Methods: A retrospective, descriptive study was conducted on 48 appendicitis patients treated at Gatot Soebroto Army Central Hospital during 2020–2021. Data were analyzed using the Mann-Whitney U test, with a significance threshold set at p<0.05. Results: Neutrophil segment counts demonstrated a statistically significant difference between complicated and uncomplicated appendicitis cases (p=0.000), with higher levels observed in complicated cases. In contrast, neutrophil stab counts, age, and gender did not show statistically significant differences (p>0.05). Conclusion: Neutrophil segment counts serve as a reliable marker for assessing appendicitis severity, while neutrophil stab counts and demographic factors such as age and gender lack predictive value. Further research is warranted to investigate the temporal dynamics of neutrophil levels and their integration with other inflammatory markers.

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Keywords: Appendicitis, biomarkers, complications, neutrophil segment, neutrophil stab

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Language : EN
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